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Table 4 Secondary outcomes

From: Retrospective case-control non-inferiority analysis of intravenous lidocaine in a colorectal surgery enhanced recovery program

 

Standard Therapy-Perioperative Lidocaine

ER Multi-Modal Analgesia-Perioperative Lidocaine

P value

Hypotensiona

 POD 1

0 (52); 0%

1 (52); 1.92%

1

 POD 2

0 (52); 0%

0 (49); 0%

-

 POD 3

0 (40); 0%

0 (10); 0%

-

 POD 4

1 (23); 4.35%

0 (5); 0%

1

Nausea and Vomitinga

 POD 1

11 (52); 21.15%

6 (52); 11.54%

0.29

 POD 2

16 (52); 30.77%

7 (49); 14.29%

0.06

 POD 3

9 (40); 22.50%

5 (10); 50%

0.12

 POD 4

8 (23); 34.78%

2 (5); 40%

1

Pruritisa

 POD 1

5 (52); 9.62%

2 (52); 0.04%

0.44

 POD 2

13 (52); 25%

2 (49); 4.08%

0.004

 POD 3

6 (40); 15%

1 (10); 10%

1

 POD 4

2 (23); 8.70%

0 (5); 0%

1

Mental status: not awake or alerta

 POD 1

4 (52); 7.69%

2 (52); 0.04%

0.68

 POD 2

6 (52); 11.54%

0 (49); 0%

0.03

 POD 3

3 (40); 7.50%

0 (10); 0%

1

 POD 4

0 (23); 0%

0 (5); 0%

-

Urinary retentiona

 POD 1

1 (52); 1.92%

6 (52); 0.12%

0.11

 POD 2

1 (52); 1.92%

3 (49); 6.12%

0.35

 POD 3

31 (40); 77.50%

6 (10); 60%

0.42

 POD 4

0 (22); 0%

1 (5); 20%

0.19

Patient Satisfaction: yesa

 POD 1

34 (52); 65.38%

38 (52); 73.08%

0.52

 POD 2

42 (52); 80.77%

40 (49); 81.63%

1

 POD 3

31 (40); 77.50%

6 (10); 60%

0.42

 POD 4

19 (23); 82.61%

1 (5); 20%

0.01

Time to ambulation (hr)bc

44.50 [22, 65.50]

20 [13.50, 25.75]

< .001

Duration of urine catheter (hr)bc

43.50 [25.75, 67.50]

27 [20, 42]

0.006

Time to bowel movement (hr)bc

40 [18, 71.50]

41.25 [28.38, 51]

0.63

Duration hospital stay (hr)bc

146 [96.75, 288]

72.25 [66.75, 114.12]

< .001

  1. aPresented as frequency, P value from χ2 or Fisher exact tests
  2. bPresented as median and (IQR), P value from Mann-Whitney U test
  3. cAll these measurements calculated from the time the patient left the operating room