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Table 2 Intraoperative blood gas and anesthetic variables in patients receiving desflurane-remifentanil or propofol-remifentanil during one-lung ventilation

From: Effect of desflurane-remifentanil vs. Propofol-remifentanil anesthesia on arterial oxygenation during one-lung ventilation for thoracoscopic surgery: a prospective randomized trial

 

TLV

15 min of OLV

30 min of OLV

45 min of OLV

60 min of OLV

Desflurane group (n = 52)

 End-tidal desflurane (vol%)

5.4 ± 1.0

6.2 ± 0.8

6.2 ± 0.8

6.2 ± 0.8

6.2 ± 0.8

 Minimum alveolar concentration

1.0 ± 0.2

1.1 ± 0.2

1.1 ± 0.2

1.1 ± 0.1

1.1 ± 0.2

 Ce, remifentanil (ng/ml)

2.3 ± 1.1

2.4 ± 0.9*

2.1 ± 1.1*

1.9 ± 1.0*

1.8 ± 1.0*

 MAP (mmHg)

84 ± 13

85 ± 15

78 ± 12*

75 ± 12*

78 ± 9*

 HR (beats/min)

68 ± 13

67 ± 11

70 ± 11

68 ± 10

69 ± 12

 BT (°C)

36.1 ± 0.4

36.1 ± 0.4

36.0 ± 0.4

35.9 ± 0.4

35.8 ± 0.5

 CVP (mmHg)

7 ± 3

8 ± 3

7 ± 3

7 ± 3

7 ± 3

 CI (l/min/m2)

2.7 ± 0.6

2.6 ± 0.6

2.9 ± 0.7

2.9 ± 0.7

2.9 ± 0.7

 Ppeak (cmH2O)

19 ± 2

22 ± 3

23 ± 4

23 ± 3

23 ± 3

 PaCO2 (mmHg)

41 ± 4

45 ± 5

45 ± 4

45 ± 4

45 ± 5

 Arterial blood pH

7.4 ± 0.0

7.4 ± 0.0

7.4 ± 0.0

7.4 ± 0.0

7.4 ± 0.0

 Base excess (mmol/l)

2.1 ± 2.2

1.9 ± 2.1

1.5 ± 2.2

1.6 ± 2.0

1.5 ± 2.1

Propofol group (n = 51)

 Ce, propofol (μg/ml)

3.6 ± 0.6

3.6 ± 0.6

3.5 ± 0.5

3.5 ± 0.5

3.6 ± 0.5

 Ce, remifentanil (ng/ml)

2.5 ± 1.2

3.0 ± 1.3*

3.1 ± 1.3*

3.2 ± 1.1*

3.3 ± 1.1*

 MAP (mmHg)

82 ± 13

85 ± 13

84 ± 10*

81 ± 10*

83 ± 10*

 HR (beats/min)

64 ± 11

65 ± 12

68 ± 12

65 ± 11

65 ± 11

 BT (°C)

36.0 ± 0.4

35.9 ± 0.4

35.9 ± 0.4

35.8 ± 0.4

35.8 ± 0.4

 CVP (mmHg)

6 ± 3

7 ± 3

7 ± 3

7 ± 4

7 ± 3

 CI (l/min/m)

2.6 ± 0.7

2.7 ± 0.7

2.8 ± 0.9

2.8 ± 0.8

2.9 ± 0.8

 Ppeak (cmH2O)

19 ± 2

21 ± 3

23 ± 3

23 ± 3

23 ± 3

 PaCO2 (mmHg)

42 ± 5

44 ± 5

45 ± 5

44 ± 5

44 ± 5

 Arterial blood pH

7.4 ± 0.0

7.4 ± 0.0

7.4 ± 0.0

7.4 ± 0.0

7.4 ± 0.0

 Base excess (mmol/l)

2.5 ± 1.9

2.3 ± 2.0

2.2 ± 2.0

2.0 ± 2.0

2.0 ± 1.9

  1. TLV two-lung ventilation, OLV one-lung ventilation, Ce effect-site concentration, MAP mean arterial pressure, HR heart rate, BT body temperature, CVP central venous pressure, CI cardiac index, P peak peak airway pressure, PaCO 2 arterial partial pressure of carbon dioxide. Values are means (SD)
  2. * p <0.05 between the groups