Desflurane group (n = 52) | Propofol group (n = 51) | p value | |
---|---|---|---|
Female | 18 (35%) | 23 (45%) | 0.277 |
Age (year) | 63 ± 8 | 62 ± 10 | 0.841 |
Body mass index (kg/m2) | 24.0 ± 2.8 | 22.9 ± 2.8 | 0.050 |
ASA class | 0.914 | ||
I | 24 (46%) | 23 (45%) | |
II | 28 (54%) | 28 (55%) | |
Smoking history | 0.257 | ||
Never smoker | 28 (54%) | 28 (55%) | |
Current smoker | 11 (21%) | 16 (31%) | |
Former smoker | 13 (25%) | 7 (14%) | |
Preoperative hemoglobin (g/dl) | 13.2 ± 1.3 | 13.2 ± 1.3 | 0.820 |
Preoperative FEV1 (% predicted) | 100.6 ± 16.3 | 103.8 ± 19.0 | 0.356 |
Preoperative FVC (% predicted) | 98.0 ± 12.6 | 100.2 ± 13.7 | 0.391 |
Preoperative PaO2 (mmHg) | 92 ± 14 | 93 ± 11 | 0.798 |
Preoperative medications | |||
Aspirin | 7 (14%) | 8 (16%) | 0.749 |
COX inhibitor other than aspirin | 2 (4%) | 4 (8%) | 0.437 |
Calcium antagonist | 12 (23%) | 11 (22%) | 0.854 |
ACE inhibitor | 0 (0%) | 1 (2%) | 0.495 |
ARB | 10 (20%) | 13 (26%) | 0.446 |
Beta blocker | 2 (4%) | 3 (6%) | 0.678 |
Diuretics | 2 (4%) | 6 (12%) | 0.160 |
OHA | 7 (14%) | 9 (18%) | 0.558 |
Clopidogrel | 0 (0%) | 2 (4%) | 0.243 |
Statin | 8 (15%) | 14 (28%) | 0.135 |
Steroid | 0 (0%) | 2 (4%) | 0.243 |
Prostacyclin | 0 (0%) | 1 (2%) | 0.495 |
Anesthesia time (min) | 222 ± 47 | 211 ± 46 | 0.243 |
Infused crystalloid (ml) | 940 ± 505 | 784 ± 378 | 0.079 |
Infused colloid (ml) | 117 ± 192 | 99 ± 167 | 0.600 |
Urinary output (ml) | 192 ± 159 | 201 ± 152 | 0.769 |
Estimated blood loss (ml) | 160 ± 89 | 143 ± 75 | 0.299 |
Extent of operation | 0.428 | ||
Lobectomy | 41 (79%) | 44 (86%) | |
Segmentectomy | 7 (13%) | 3 (6%) | |
Wedge resection | 4 (8%) | 4 (8%) | |
Mainly resected lobe | 0.747 | ||
Right upper lobe | 16 (31%) | 15 (29%) | |
Right middle lobe | 3 (6%) | 7 (14%) | |
Right lower lobe | 13 (25%) | 12 (23%) | |
Left upper lobe | 10 (19%) | 8 (16%) | |
Left lower lobe | 10 (19%) | 9 (18%) |