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Table 1 Characteristics of patients receiving desflurane-remifentanil or propofol-remifentanil during one-lung ventilation for thoracoscopic surgery

From: Effect of desflurane-remifentanil vs. Propofol-remifentanil anesthesia on arterial oxygenation during one-lung ventilation for thoracoscopic surgery: a prospective randomized trial

 

Desflurane group (n = 52)

Propofol group (n = 51)

p value

Female

18 (35%)

23 (45%)

0.277

Age (year)

63 ± 8

62 ± 10

0.841

Body mass index (kg/m2)

24.0 ± 2.8

22.9 ± 2.8

0.050

ASA class

  

0.914

 I

24 (46%)

23 (45%)

 

 II

28 (54%)

28 (55%)

 

Smoking history

  

0.257

 Never smoker

28 (54%)

28 (55%)

 

 Current smoker

11 (21%)

16 (31%)

 

 Former smoker

13 (25%)

7 (14%)

 

Preoperative hemoglobin (g/dl)

13.2 ± 1.3

13.2 ± 1.3

0.820

Preoperative FEV1 (% predicted)

100.6 ± 16.3

103.8 ± 19.0

0.356

Preoperative FVC (% predicted)

98.0 ± 12.6

100.2 ± 13.7

0.391

Preoperative PaO2 (mmHg)

92 ± 14

93 ± 11

0.798

Preoperative medications

 Aspirin

7 (14%)

8 (16%)

0.749

 COX inhibitor other than aspirin

2 (4%)

4 (8%)

0.437

 Calcium antagonist

12 (23%)

11 (22%)

0.854

 ACE inhibitor

0 (0%)

1 (2%)

0.495

 ARB

10 (20%)

13 (26%)

0.446

 Beta blocker

2 (4%)

3 (6%)

0.678

 Diuretics

2 (4%)

6 (12%)

0.160

 OHA

7 (14%)

9 (18%)

0.558

 Clopidogrel

0 (0%)

2 (4%)

0.243

 Statin

8 (15%)

14 (28%)

0.135

 Steroid

0 (0%)

2 (4%)

0.243

 Prostacyclin

0 (0%)

1 (2%)

0.495

Anesthesia time (min)

222 ± 47

211 ± 46

0.243

Infused crystalloid (ml)

940 ± 505

784 ± 378

0.079

Infused colloid (ml)

117 ± 192

99 ± 167

0.600

Urinary output (ml)

192 ± 159

201 ± 152

0.769

Estimated blood loss (ml)

160 ± 89

143 ± 75

0.299

Extent of operation

  

0.428

 Lobectomy

41 (79%)

44 (86%)

 

 Segmentectomy

7 (13%)

3 (6%)

 

 Wedge resection

4 (8%)

4 (8%)

 

Mainly resected lobe

  

0.747

 Right upper lobe

16 (31%)

15 (29%)

 

 Right middle lobe

3 (6%)

7 (14%)

 

 Right lower lobe

13 (25%)

12 (23%)

 

 Left upper lobe

10 (19%)

8 (16%)

 

 Left lower lobe

10 (19%)

9 (18%)

 
  1. FEV 1 forced expiratory volume in 1 s, FVC forced vital capacity, PaO 2 arterial partial pressure of oxygen, COX cyclooxygenase, ACE angiotensin converting enzyme, ARB angiotensin receptor blocker, OHA oral hypoglycemic agent. Preoperative FEV1 and FVC are expressed as percentages of the predicted value. Values are numbers (%) or means (SD)