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Table 5 Exploratory analyses - Comparison of sugammadex and neostigmine on OR efficiency and clinical outcomes in an OR over 1 month when deep block is maintained to the end of all procedures [0% of patients verified to have full neuromuscular recovery (TOF ratio ≥ 0.9) prior to extubation]

From: A discrete event simulation model of clinical and operating room efficiency outcomes of sugammadex versus neostigmine for neuromuscular block reversal in Canada

Outcome Measure

Neostigmine

Sugammadex (4 mg/kg)

Minutes of OR time saved per procedure

15

30

45

60

OR efficiency outcomes

 Number of OR minutes saved per day

39

79

118

158

 % of days all procedures are completed within the regular OR day

46.7%

61.9%

77.1%

86.9%

91.4%

 Number of procedures performed

54.5

54.7

55.1

55.1

55.2

 Procedures cancelled due to lack of OR time

1.2

0.7

0.4

0.4

0.3

 Procedures cancelled for other reasons

7.3

7.6

7.6

7.6

7.6

 Paid hours of staff over-time

84.1

54.9

32.0

18.3

11.5

Clinical outcomes

 Cases of residual blockade avoided

30

30

30

30

 Hypoxemia cases avoideda

7

7

7

7

 Upper airway obstruction cases avoideda

13

13

13

13

 Absolute reduction in risk of residual blockade, per patient

56%

56%

56%

56%

  1. OR Operating room
  2. aIncludes both cases which are and are not clinically diagnosed and managed