| |
p - value | HR | 95 % CI |
|---|
CCI | 0.023* | 1.08 | 1.010–1.149 |
OI on day 3 (per point) | <0.001* | 1.03 | 1.015–1.047 |
Age (per year) | 0.003* | 1.02 | 1.006–1.029 |
TISS28 on admission | 0.006* | 1.02 | 1.007–1.043 |
Crs on day 3 | 0.003* | 0.98 | 0.971–0.994 |
Prone position on day 3 | 0.002* | 0.81 | 0.711–0.928 |
BMI | 0.097 | 0.98 | 0.956–1.004 |
pH on day 3 | 0.002* | 0.03 | 0.002–0.275 |
- Parameters considered in the multivariate regression model using backwards selection that had significant impact in univariate analyses: age, BMI, Charlson comorbidity index (CCI), ICU admission scores (APACHE II, SOFA, TISS28), ELAD (yes/no) as well as clinical variables that were assessed on day 3 (SOFA score), Crs Compliance of respiratory system by Crs = VT/ (Pplat - Pmean) pH day 3, Vt/PBW, Ppeak, Prone position, categories of Berlin definition and AECC definition, PaO2/FiO2. Data of 341 patients were considered. * p < 0,05. All parameters of the final regression model are presented, regardless of their significance
-
BMI Body Mass Index, CCI Charlson comorbidity index, CI confidence interval, ELAD extracorporeal lung assist devices (including extracorporeal lung assist (ECLA) and extracorporeal membrane oxygenation (ECMO), F
i
O
2
inspiratory fraction of oxygen, HR Hazard Ratio, OI oxygenation index, PBW predicted body weight, P
peak
peak airway pressure, TISS Therapeutic Intervention Scoring System
