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Table 1 Patient characteristics and comparison between survivors and non-survivors at diagnosis of acute respiratory distress syndrome

From: Predictors of survival in critically ill patients with acute respiratory distress syndrome (ARDS): an observational study

 

All patients

Survivor

Non-survivor

p - value

n = 442

n = 240

n = 202

Basic characteristics

 Age [years]

50.0 (37.0;61.0)

46.0 (34.0;60.0)

53.0 (42.0;64.0)

0.001*

 Sex (male)

285 (64.5 %)

158 (55.4 %)

127 (44.6 %)

0.602

 Weight [kg]

80.0 (70.0;95.0)

83.0 (70.0;100)

80.0 (69.5;90.0)

0.001*

 Body mass index [kg/m2]

28.4 (8.46)

29.6 (8.81)

26.8 (7.73)

0.001*

 Transfer from other hospital

307 (69.5 %)

165 (53.7 %)

142 (46.3 %)

0.878

 LOS hospital before admission [d]

7.0 (3.0;15.0)

6.0 (3.0;10.2)

11.0 (4.0;23.0)

<0.001*

 LOS ICU before admission [d]

4.0 (2.0;11.0)

4.0 (2.0;7.0)

6.0 (2.0;13.5)

0.002*

 Duration of mechanical ventilation before admission [d]

3.0 (2.0;7.0)

3.0 (2.0;6.0)

4.0 (2.0;11.0)

0.002*

Severity of illness, organ failure and comorbidities on ICU admission

 APACHE II

28.0 (20.0;35.0)

25.0 (18.0;35.2)

29.0 (24.0;37.0)

<0.001*

 SAPS II

54.0 (39.0;70.0)

49.0 (37.0;63.0)

61.0 (42.5;73.0)

<0.001*

 TISS

50.0 (43.0;58.0)

47.0 (42.0;56.0)

53.0 (45.0;59.0)

<0.001*

 SOFA

12.0 (9.0;15.0)

11.0 (9.0;14.0)*

13.0 (9.0;16.0)*

<0.001*

 CCI

3.0 (2.0–5.0)*

3.0 (2.0–5.0)*

4.0 (3.0–6.0)*

<0.001*

Aetiology of ARDS

   

0.137

 - Pneumonia

242 (54,7 %)

133 (55.0 %)

109 (45.0 %)

 - Immuninsufficiency

67 (15.1 %)

30 (44.8 %)

37 (55.2 %)

 - Acute on chronic

55 (12.4 %)

26 (47.3 %)

29 (52,7 %)

 - Trauma

29 (6,6 %)

20 (69.0 %)

9 (31.0 %)

 - Sepsis of extrapulmonary origin

27 (6.1 %)

17 (63.0 %)

10 (37.0 %)

 - Other

22 (5.0 %)

14 (63.3 %)

8 (36.7 %)

Severity of lung failure (assessed on day1)

 AECC Definition

   

0.170

  ALI

99 (22.4 %)

60 (60.6 %)

39 (39.4 %)

  ARDS

343 (77.6 %)

180 (52.5 %)

163 (47.5 %)

 Berlin Definition

   

0.149

  Mild

99 (22.4 %)

60 (60.6 %)

39 (39.4 %)

  Moderate

210 (47.5 %)

117 (55.7 %)

93 (44.3 %)

  Severe

133 (30.1 %)

63 (47.4 %)

70 (52.6 %)

 PaO2/FiO2 [mmHg]

137 (92;193)

142 (95;199)

123 (89;178)

0.026*

 Oxygenation index (OI)

16.9 (11.6;27.4)

16.4 (11.1;25.9)

18.5 (12.6;28.2)

0.063

Extracorporeal lung assist devices (ELAD)

   

<0.001*

 No ELAD

186 (42.1 %)

130 (69.9 %)

56 (30.1 %)

 With ELAD

256 (57.9 %)

110 (43.0 %)

146 (57.0 %)

  - Only ECMO

146 (33.0 %)

61 (41.8 %)

85 (58.2 %)

  - Only ECLA

74 (16.7 %)

34 (46.0 %)

40 (54.0 %)

  - ECLA + ECMO

36 (8.14 %)

15 (41.7 %)

21 (58.3 %)

  1. Discrete variables are presented as number of percentage and were analysed with Chi square test for nonparametric samples. Continuous variables are presented as median and 25/75 percentiles and were analysed with Mann–Whitney-U-Test for nonparametric samples. * p < 0,05
  2. APACHE II Acute Physiology And Chronic Health Evaluation II, d days, ICU intensive care unit, LOS length of stay, SAPS II Simplified Acute Physiology Score II, SOFA Sequential Organ Failure Assessment, TISS Therapeutic Intervention Scoring System, CCI Charlson comorbidity index, F i O 2 inspiratory fraction of oxygen, iNO inhalative nitric oxide, PBW predicted body weight, P a CO 2 arterial partial pressure of carbon dioxide, P a O 2 arterial partial pressure of oxygen, PEEP positive end-expiratory pressure, P mean mean airway pressure, P peak peak airway pressure, V t tidal volume, ECLA extracorporeal lung assist, ECMO extracorporeal membrane oxygenation, ELAD extracorporeal lung assist devices. Complete data on hospital stay in referring institutions was available for 309 patients
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BMC Anesthesiology

ISSN: 1471-2253

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