Effect of the severity of liver dysfunction on the minimum alveolar concentration of sevoflurane responding to an electronic stimulation in cirrhotic patients

Table 5 BIS value and vital signs during the study

	Group N	Group A	Group B	P-value
Before anesthesia
HR (beat/min)	76 (63,92)	83.5 (71,122)	82.5 (65,118)	0.15
SpO₂ (%)	98.3 ± 1.06	97.7 ± 1.25	97.3 ± 1.83	0.3
MAP (mmHg)	82.7 ± 14.22	87.2 ± 32.05	78.9 ± 9.04	0.104
BIS	97 (97,99)	97 (94,97)	94 (87,97)^a	<0.001
Time of MAC_electric1
HR (beat/min)	63.6 ± 7.20	76.2 ± 7.24^a	71.4 ± 11.21	0.012
SpO₂ (%)	100 (99,100)	100 (99,100)	100 (99,100)	0.631
MAP (mmHg)	65 (54,85)	75 (61,89)	64 (60,79)^a	0.028
BIS	46.4 ± 6.69	49.1 ± 9.36	46.4 ± 6.59	0.665
Time of MAC_electric2
HR (beat/min)	65.9 ± 7.05	80.7 ± 7.10^a	73.7 ± 11.26	0.003
SpO₂ (%)	100 (99,100)	100 (99,100)	100 (99,100)	0.631
MAP (mmHg)	67 (57,90)	85 (77,103)^a	65.5 (62,84)^b	0.001
BIS	52.3 ± 7.32	56.1 ± 9.13	51.2 ± 11.59	0.519

Time of MAC_electric 1: The time when the lowest end-tidal concentration of sevoflurane that prevented purposeful movement was determined
Time of MAC_electric2: The time when the highest end-tidal concentration of sevoflurane that did not prevent purposeful movement was determined
Abbreviations: HR heart rate, SpO2 pulse oximetry, MAP mean arterial pressure, BIS bispectral index
^aCompared with Group N, P < 0.05
^bCompared with Group A, P < 0.05

ISSN: 1471-2253