Skip to main content
Fig. 3 | BMC Anesthesiology

Fig. 3

From: Sevoflurane and isoflurane inhibit KCl-induced Class II phosphoinositide 3-kinase α subunit mediated vasoconstriction in rat aorta

Fig. 3

Effects of sevoflurane and isoflurane on KCl-induced contraction in rat aortic smooth muscle. The aortas rings were incubated in the presence of 1.7 %, 3.4 %, 5.1 % sevoflurane (SEVO) or 1.2 %, 2.3 %, 3.5 % isoflurane (ISO), or 1 mM LY294002, or 1 uM Y27632 for 15 min before and during exposure to KCl. Isometric tension development in response to anesthetic or inhibitor was expressed as percentage relative to that induced by KCl. * P < 0.05, ** P < 0.01 versus the value in the presence of KCl without anesthetics or inhibitor (n = 7, each)

Back to article page

BMC Anesthesiology

ISSN: 1471-2253

Contact us