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Table 2 Parameters regarding to quality of sedation/analgesia

From: Dexmedetomidine-ketamine versus Dexmedetomidine-midazolam-fentanyl for monitored anesthesia care during chemoport insertion: a Prospective Randomized Study

 

Group DK (n = 25)

Group DMF (n = 27)

P value

Onset time of sedation (min)

6.98 ± 6.33

5.94 ± 4.40

0.50

Patient requiring rescue sedatives [n (%)]

6 (24.0 %)

0 (0.0 %)*

0.009

Patient requiring rescue analgesics [n (%)]

6 (24.0 %)

4 (14.8 %)

0.492

Modified OAA/S score = 2 [n (%)]

10 (40.0 %)

21 (77.8 %)*

0.006

Duration of MAC (min)

28.8 ± 5.5

28.6 ± 4.4

0.903

Total dose of dexmedetomidine (μg)

102.2 ± 24.3

100.6 ± 14.2

0.770

Patient requiring rescue drug for hypotension [n (%)]

7 (28.0 %)

3 (11.1 %)

0.167

Patient requiring rescue drug for bradycardia [n (%)]

3 (12.0 %)

0 (0.0 %)

0.104

  1. Data are presented as number (%) or mean ± SD
  2. *P < 0.05, compared with group DK
  3. Group DK dexmedetomidine-ketamine group, group DMF dexmedetomidine-midazolam-fentanyl group, modified OAA/S score modified Observer’s Assessment of Analgesia and Sedation score, MAC monitored anesthesia care