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Table 1 Demographic and clinical characteristics of the UNOS liver transplantation sample for the time interval 2000-2012 by portal vein Thrombosis and graft failure ascribed to vascular thrombosis

From: Autoimmune conditions are associated with perioperative thrombotic complications in liver transplant recipients: A UNOS database analysis

  Preoperative Portal Vein Thrombosis Postoperative Vascular Thrombosis
Demographic Characteristics Yes (N = 4,247) No (N = 61,399) P-value Yes (N = 1,233) No (N = 6,824) P-value
Age (year) 54.1 52.4 <0.0001* 49.8 50.5 0.04*
Sex (Male) (%) 2,952 (69.5 %) 40,893 (66.6 %) <0.0001* 834 (67.6 %) 4,559 (66.8 %) 0.58
BMI
 Underweight (%) (BMI < 18.5 kg/m2) 104 (2.5 %) 1,498 (2.4 %) 0.97 51 (4.1 %) 173 (2.5 %) 0.002*
 Overweight (%) (≥25 kg/m2) 1,418 (33.4 %) 21,605 (35.2 %) 0.018* 401 (32.5 %) 2,454 (36.0 %) 0.02*
 Obese (%) (BMI ≥ 30 kg/m2) 1,549 (36.5 %) 20,003 (32.6 %) <0.0001* 392 (31.8 %) 2,184 (32 %) 0.90
Clinical Factors
 TIPSS (%) at the time of LTX 502 (11.8 %) 5,156 (8.4 %) <0.0001* 93 (7.5 %) 510 (7.5 %) 0.06
 Portal Hypertensive Bleeding (%) at time of LTX 73 (8.8 %) 636 (4.4 %) <0.0001* 9 (2.8 %) 129 (6.7 %) 0.02*
 Portal Vein Thrombosis (%) at the time of LTX -- -- -- 136 (11.0 %) 373 (5.4 %) <0.0001*
 Diabetes mellitus (%) 925 (23.9 %) 8,586 (15.5 %) <0.0001* 140 (12.7 %) 700 (11.7 %) 0.39
 Autoimmune Cirrhosis (%) 135 (3.2 %) 1,607 (2.6 %) 0.03* 42 (3.8 %) 165 (2.7 %) 0.05*
 Primary Sclerosing Cholangitis (%) -- -- -- 97 (7.9 %) 288 (4.2 %) <0.0001*
 Primary Biliary Cirrhosis (%) -- -- -- 48 (4.3 %) 158 (2.6 %) 0.002*
 Hepatocellular carcinoma (%) 146 (3.8 %) 1,809 (3.2 %) 0.05* 23 (2.0 %) 258 (2.5 %) 0.33
  1. *p-values indicate a statistically significant difference at α = 0.05
  2. LTX Liver transplantation