Skip to main content

Table 1 Demographic and clinical characteristics of the UNOS liver transplantation sample for the time interval 2000-2012 by portal vein Thrombosis and graft failure ascribed to vascular thrombosis

From: Autoimmune conditions are associated with perioperative thrombotic complications in liver transplant recipients: A UNOS database analysis

 

Preoperative Portal Vein Thrombosis

Postoperative Vascular Thrombosis

Demographic Characteristics

Yes (N = 4,247)

No (N = 61,399)

P-value

Yes (N = 1,233)

No (N = 6,824)

P-value

Age (year)

54.1

52.4

<0.0001*

49.8

50.5

0.04*

Sex (Male) (%)

2,952 (69.5 %)

40,893 (66.6 %)

<0.0001*

834 (67.6 %)

4,559 (66.8 %)

0.58

BMI

 Underweight (%) (BMI < 18.5 kg/m2)

104 (2.5 %)

1,498 (2.4 %)

0.97

51 (4.1 %)

173 (2.5 %)

0.002*

 Overweight (%) (≥25 kg/m2)

1,418 (33.4 %)

21,605 (35.2 %)

0.018*

401 (32.5 %)

2,454 (36.0 %)

0.02*

 Obese (%) (BMI ≥ 30 kg/m2)

1,549 (36.5 %)

20,003 (32.6 %)

<0.0001*

392 (31.8 %)

2,184 (32 %)

0.90

Clinical Factors

 TIPSS (%) at the time of LTX

502 (11.8 %)

5,156 (8.4 %)

<0.0001*

93 (7.5 %)

510 (7.5 %)

0.06

 Portal Hypertensive Bleeding (%) at time of LTX

73 (8.8 %)

636 (4.4 %)

<0.0001*

9 (2.8 %)

129 (6.7 %)

0.02*

 Portal Vein Thrombosis (%) at the time of LTX

--

--

--

136 (11.0 %)

373 (5.4 %)

<0.0001*

 Diabetes mellitus (%)

925 (23.9 %)

8,586 (15.5 %)

<0.0001*

140 (12.7 %)

700 (11.7 %)

0.39

 Autoimmune Cirrhosis (%)

135 (3.2 %)

1,607 (2.6 %)

0.03*

42 (3.8 %)

165 (2.7 %)

0.05*

 Primary Sclerosing Cholangitis (%)

--

--

--

97 (7.9 %)

288 (4.2 %)

<0.0001*

 Primary Biliary Cirrhosis (%)

--

--

--

48 (4.3 %)

158 (2.6 %)

0.002*

 Hepatocellular carcinoma (%)

146 (3.8 %)

1,809 (3.2 %)

0.05*

23 (2.0 %)

258 (2.5 %)

0.33

  1. *p-values indicate a statistically significant difference at α = 0.05
  2. LTX Liver transplantation