Coagulation competence for predicting perioperative hemorrhage in patients treated with lactated Ringer’s vs. Dextran - a randomized controlled trial

Table 3 Comparison of the coagulation variables between the study groups

Variable	Dextran (n = 19)		Lactated Ringer’s (n = 18)		P value
Reaction time (min)
T₁	5.93	5.34–6.54	5.25	4.69–5.82	0.100
T₂	5.85	5.34–6.36	4.70	4.19–5.22	0.002
T₃	5.90	5.20–6.59	4.26**	3.83–4.70	0.001
T₄	5.91	5.36–6.45	4.31*	3.74–4.89	0.001
Angle (°)
T₁	70.72	68.76–72.68	71.12	68.03–74.21	0.817
T₂	60.87***	56.85–64.90	72.84	70.56–75.12	0,000
T₃	54.92***	50.53–59.30	72.57	69.95–75.18	0,000
T₄	58.92***	55.01–62.82	72.39	70.32–74.46	0,000
Maximal amplitude (mm)
T₁	65.17	61.93–68.42	63.98	60.25–67.72	0.614
T₂	54.30***	49.53–59.08	64.39	61.39–67.40	0.001
T₃	48.92***	44.65–53.19	62.08	58.9–65.27	0.000
T₄	49.08***	44.83–53.34	63.11	52.33–59.09	0.000
Lysis after 30 min (%)
T₁	1.52	0.64–2.42	2.15	0.82–3.50	0.403
T₂	1.17	0.31–2.04	1.69	0.57–2.80	0.444
T₃	0.71	0.27–1.15	1.57	0.71–2.42	0.066
T₄	1.05	0.21–1.89	2.30	0.63–3.97	0.146

TEG analysis after induction of anesthesia (T₁); after resection of the urinary bladder (T₂); at the end of surgery (T₃), and 2 h thereafter in the recovery room (T₄). Values are mean with 95 % confidence interval. P-value by univariate analysis
*P <0.05, **P <0.01 and ***P <0.001 difference from induction of anesthesia (T1) within the group

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