Tissue oxygen saturation as an early indicator of delayed lactate clearance after cardiac surgery: a prospective observational study

Kopp, Rüdger; Dommann, Katja; Rossaint, Rolf; Schälte, Gereon; Grottke, Oliver; Spillner, Jan; Rex, Steffen; Marx, Gernot

doi:10.1186/s12871-015-0140-7

Table 2 Haemodynamics, gas exchange and metabolic state of patients

From: Tissue oxygen saturation as an early indicator of delayed lactate clearance after cardiac surgery: a prospective observational study

	T −1	T 0	T 1	T 4	T d1
	After induction of anaesthesia	After surgery	1 hour after surgery	4 hours after surgery	Day 1
StO₂ (%)	85 (4)*	86 (6)**	76 (7)^,^,**	75 (6)^,^,***	84 (5)*^,**
THI	13.5 (1.8)*	13.5 (2.0)**	12.6 (1.6)^,*	12.4 (1.5)^,*	12.6 (2.1)^,*
Heart rate (min⁻¹)	64 (12)*	87 (9)*	88 (8)*	91 (8)*	91 (9)*
MAP (mmHg)	84 (15)	80 (12)	81 (12)	77 (11)	82 (15)
MPAP (mmHg)	24 (8)	25 (11)	26 (6)***	27 (7)****	22 (7)*^,**
CVP (mmHg)	12 (4)*	12 (5)**	12 (3)	12 (4)****	9 (4)^,^,***
PCWP (mmHg)	16 (6)*	13 (5)**	11 (4)^,^,**	11 (4)^,^,***	8 (5)^,^,^,**
CI (L min⁻¹ m⁻²)	2.0 (0.4)*	2.5 (0.7)^,*	2.1 (0.7)^,*	2.4 (0.6)*	2.7 (0.8)^,**
Body temperature (°C)	36.0 (0.5)*	36.0 (0.8)**	35.4 (0.9)^,^,**	36.3 (0.9)*^,**	37.2 (0.5)^,^,^,**
FiO₂	0.9 (0.2)*	1.0 (0.0)**	0.6 (0.1)^,^,**	0.4 (0.1)^,^,**	0.3 (0.1)^,^,**
Haemoglobin (g · dl⁻¹)	12.8 (1.5)*	9.8 (1.5)*	9.3 (1.5)^,*	10.0 (1.1)*	10.5 (1.2)^,*
S_aO₂ (%)	100 (0)*	100 (0)**	99 (1)***	98 (3)^,^,**	97 (2)^,^,**
P_aO₂ (mmHg)	354 (128)*	368 (121)**	210 (88)^,^,**	127 (47) ^,^,**	103 (31) ^,^,**
Arterial pH	7.42 (0.05)*	7.38 (0.05)^,*	7.39 (0.08)***	7.33 (0.07)^,^,^,**	7.37 (0.05)^,***
Base Deficit	0.3 (2.5)*	−2.0 (3.9)*	−2.0 (2.6)*	−2.3 (2.9)*	−2.3 (2.5)*
S_vO₂ (%)	81 (8)*	72 (9)*	71 (8)*	67 (9)*	67 (7)*
Lactate (mmol · L⁻¹)	0.58 (0.21)*	1.1 (0.84)^,*	1.39 (1.24)*	1.69 (1.61)^,*	1.46 (0.77)*
Lactate clearance (%)	38 (24)*	0 (0)*^,†	−26 (49)*	−55 (112)^,*	−51 (74)^,*
Norepinephrine (μg kg⁻¹ min⁻¹)	0.00 (0.00)*	0.03 (0.06)*	0.05 (0.08)^,**	0.05 (0.09)^,***	0.02 (0.07)*^,**
Epinephrine (μg kg⁻¹ min⁻¹)	0.00 (0.00)*	0.01 (0.02)	0.01 (0.03)*	0.01 (0.03)	0.00 (0.01)

StO ₂, tissue oxygen saturation, THI total haemoglobin index, MAP mean arterial pressure, MPAP mean pulmonary artery pressure, CVP central venous pressure, PCWP pulmonary capillary wedge pressure, CI Cardiac index, FiO ₂ fraction of inspired oxygen, S _a O2 arterial oxygen saturation, P _a O ₂ arterial partial oxygen pressure, S _v O2 mixed venous oxygen saturation
Data is presented as mean (SD) and p <0.05 was considered significant between time points: * T −1 vs. T 0-T d1, ** T 0 vs. T1-T d1, *** T 1 vs. T 4-T d1, **** T 4 vs. T d1

Back to article page

ISSN: 1471-2253

Contact us

Submission enquiries: bmcanesthesiology@biomedcentral.com
General enquiries: ORSupport@springernature.com

BMC Anesthesiology

Contact us