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Fig. 2 | BMC Anesthesiology

Fig. 2

From: Pretreatment but not subsequent coincubation with midazolam reduces the cytotoxicity of temozolomide in neuroblastoma cells

Fig. 2

Effect of pretreatment and coincubation with midazolam to temozolomide induced toxicity. Cell viability of neuroblastoma (SHEP) cells was measured using the XTT assay after incubation with increasing concentrations of temozolomide (24 h). Black circles: relative cell viability after incubation with TMZ (10, 30, 100, 300, 1000, 2000 μM); greys squares: pretreatment with midazolam (16 μM) for 6 h with subsequent incubation with increasing concentrations of temozolomide; white triangles: pretreatment with midazolam (16 μM) followed by coincubation with temozolomide (24 h) (n = 5; data are expressed as mean ± SD)

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BMC Anesthesiology

ISSN: 1471-2253

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