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Fig. 3 | BMC Anesthesiology

Fig. 3

From: Preemptive perineural bupivacaine attenuates the maintenance of mechanical and cold allodynia in a rat spinal nerve ligation model

Fig. 3

No effect of spinal nerve ligation or bupivacaine on thermal hyperalgesia. Paw withdrawal latency to a noxious thermal stimulus applied to the ipsilateral (a) and contralateral (b) hindpaw. Responses were recorded prior to and 3, 7, 10, 14 and 21 days following bupivacaine (n = 7) or saline (n = 6) treatment prior to spinal nerve ligation. A sham (n = 3) group was also tested. Asterisks denote significant main effect of treatment detected by two-way ANOVA and Tukey’s posthoc analysis

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