Fig. 2
H2S up-regulation of NR2A activates the pro-survival CREB signaling pathway. a. Extracts from sham or treatment groups were immunoblotted with antibodies against phosphorylated-CREB (p-CREB). β-actin was used as a loading control. b. Expression levels of p-CREB were quantified and plotted relative to those of sham operation group (Sh) for each protein. *, P < 0.05 compared to Sh, #, P < 0.05 compared to NT (LSD-t test) c. qRT-PCR was used to assess levels of BDNF in total hippocampal RNA extracts from sham operation and treated groups. *, P < 0.05 compared to Sh, #, P < 0.05 compared to NT (LSD-t test)