Using clinical parameters to guide fluid therapy in high-risk thoracic surgery. A retrospective, observational study

Table 2 Volumes of administered fluids and fluid balances during and after extrapleural pneumonectomy^a

	Intra-operative			ICU on the day of operation
	Before group (n = 18)	After group (n = 12)	P value	Before group (n = 18)	After group (n = 12)	P value
Red blood cells^b	300 (0; 1200)	0 (0; 600)		0 (0; 600)	0 (0; 300)
Fresh frozen plasma^b	0 (0; 600)	0 (0; 600)		0 (0; 600)	None
Colloids	950 (500; 1750)	500 (0; 1500)		550 (0; 1500)	500 (0; 1500)
Crystalloids	1150 (500; 2500)	1000 (500; 1500)		1713 (625; 3075)	1513 (325; 1975)
Total volume of administered fluid	2675 (1000; 5350)	1600 (600; 3600)	0.01	2588 (1400; 4925)	1810 (825; 3525)	0.04
Fluid balances^c	779 (−429; 1863)	−385 (−2130; 10)	0.0003	176 (−970; 1567)	111 (−419; 287)	0.26

All values are given in ml, as median (range). Colloids are dextran, hydroxyethyl starch or 5 % human albumin. Crystalloids are isotonic solutions of crystalloids with or without glucose
ICU Intensive Care Unit; ml millilitres
^aThirty patients divided in two groups according to whether they had surgery before or after changes in standard therapy, ^bOne unit = 300 ml, ^cThe calculations in both groups included insensible perspiration of 1 ml/kg/hour

ISSN: 1471-2253