Fluid treatment | Group 1 | Group 2 | Group 3 | Group 4 | ANOVA |
---|---|---|---|---|---|
Preloading 500 ml | No | Yes | No | No | |
Bolus infusion 9 ml/kg before surgery | Starch | Starch | Starch | Ringer | |
Continuous infusion 12 ml/kg/1 hr | Starch | Ringer | Ringer | Ringer | |
Cardiac output (L/min) | |||||
Before anaesthesia | 5.8 (1.6) | 6.1 (1.6) | 7.1 (2.2) | 6.2 (1.4) | NS |
Beginning of surgery | 3.5 (0.7) | 3.6 (0.6) | 3.6 (0.7) | 3.1 (0.4) | P< 0.03 |
1 hour of surgery | 5.0 (1.4) | 4.5 (1.4) | 4.8 (1.6) | 4.6 (1.3) | NS |
Relative to before anaesthesia (%) | s | ||||
After bolus infusions | 63 (19) | 61 (16) | 55 (19) | 53 (13) | NS |
1 hour of surgery | 90 (24) | 75 (18) | 70 (23) | 78 (20) | P< 0.03 |
Mean arterial pressure (mmHg) | |||||
Before anaesthesia | 101 (13) | 106 (14) | 107 (12) | 109 (10) | NS |
Beginning of surgery | 71 (10) | 76 (91) | 70 (8) | 70 (11) | NS |
1 hour of surgery | 92 (16) | 95 (16) | 97 (31) | 93 (19) | NS |
Relative to before anaesthesia (%) | |||||
Beginning of surgery | 70 (9) | 72 (10) | 66 (8) | 65 (10) | P< 0.03 |
1 hour of surgery | 92 (16) | 90 (16) | 92 (31) | 86 (19) | NS |
Heart rate (bpm) | |||||
Before anaesthesia | 75 (11) | 79 (14) | 84 (18) | 72 (9) | NS |
Beginning of surgery | 59 (7) | 56 (8) | 56 (8) | 55 (8) | NS |
1 hour of surgery | 64 (9) | 56 (10) | 61 (11) | 60 (9) | P< 0.03 |
Relative to before anaesthesia (%) | |||||
Beginning of surgery | 73 (10) | 72 (15) | 69 (12) | 78 (8) | NS |
1 hour of surgery | 88 (19) | 73 (14) | 74 (18) | 86 (14) | P< 0.002 |