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Table 1 Details of patients, surgeries and fluid treatment, selected blood parameters and outcome measures

From: Ringer’s lactate, but not hydroxyethyl starch, prolongs the food intolerance time after major abdominal surgery; an open-labelled clinical trial

Fluid treatment

Group 1

Group 2

Group 3

Group 4

ANOVA

Preloading 500 ml

No

Yes

No

No

Bolus infusion 9 ml/kg

Starch

Starch

Starch

Ringer

Continuous infusion 12 ml/kg/1 hr

Starch

Ringer

Ringer

Ringer

N

20

28

18

22

 

Age (years)

62 (10)

58 (13)

56 (12)

63 (8)

NS

Body weight (kg)

59 (7)

59 (8)

62 (8)

58 (8)

NS

Males (per cent)

75

54

72

77

 

Gastric/colonic/rectal cancer (N)

11/2/7

5/9/14

0/7/11

17/3/2

 

Open surgery (N)

5

4

5

1

 

Anaesthesia time (min)

262 (96)

272 (62)

269 (60)

242 (65)

NS

Operating time (min)

206 (97)

201 (64)

206 (63)

195 (62)

NS

Blood loss (ml)

205 (138)

160 (114)

200 (89)

194 (114)

NS

Urine output (ml)

516 (402)

557 (168)

441 (286)

361 (156)

NS

Starch (ml)

1125 (235)

1018 (94)

1000 (0)

420 (179)

P < 0.001

Ringer’s lactate (ml)

1475 (472)

1438 (534)

1333 (542)

2295 (480)

P < 0.001

Erythrocytes (N; ml)

5; 420 (277)

1; 700

1; 300

6; 454 (282)

 

Plasma (N; ml)

0

1; 500

1; 230

3; 417 (40)

 

Blood haemoglobin (g/L)

     

   Before surgery

128 (17)

124 (24)

127 (24)

124 (22)

NS

   After surgery

112 (15)

115 (15)

113 (19)

111 (16)

NS

Serum creatinine (μmol/L)

     

   Before surgery

69 (13)

68 (17)

65 (14)

75 (14)

NS

   After surgery

63 (12)

61 (18)

58 (12)

64 (10)

NS

Time in PACU (min)

71 (25)

60 (23)

66 (34)

97 (40)

P < 0.001

Paralytic ileus (days)

3.2 (0.9)

3.6 (1.4)

2.7 (0.9)

3.5 (1.1)

P = 0.054

Food intolerance (days)

4.5 (1.9)

4.6 (1.9)

4.6 (2.4)

6.5 (3.5)

P < 0.03

Complications per operation

0.35

0.36

0.28

0.23

NS

Infectious complications (N)

5

2

3

1

 

Bleeding complications (N)

1

3

1

1

 

Length of hospital stay (days)

13.0 (4.6)

13.9 (2.6)

13.3 (3.0)

13.3 (4.7)

NS

  1. Data are the mean (SD) or the actual number (N) of patients. NS = not statistically significant.