Fluid treatment | Group 1 | Group 2 | Group 3 | Group 4 | ANOVA |
---|---|---|---|---|---|
Preloading 500 ml | No | Yes | No | No | |
Bolus infusion 9 ml/kg | Starch | Starch | Starch | Ringer | |
Continuous infusion 12 ml/kg/1 hr | Starch | Ringer | Ringer | Ringer | |
N | 20 | 28 | 18 | 22 | |
Age (years) | 62 (10) | 58 (13) | 56 (12) | 63 (8) | NS |
Body weight (kg) | 59 (7) | 59 (8) | 62 (8) | 58 (8) | NS |
Males (per cent) | 75 | 54 | 72 | 77 | |
Gastric/colonic/rectal cancer (N) | 11/2/7 | 5/9/14 | 0/7/11 | 17/3/2 | |
Open surgery (N) | 5 | 4 | 5 | 1 | |
Anaesthesia time (min) | 262 (96) | 272 (62) | 269 (60) | 242 (65) | NS |
Operating time (min) | 206 (97) | 201 (64) | 206 (63) | 195 (62) | NS |
Blood loss (ml) | 205 (138) | 160 (114) | 200 (89) | 194 (114) | NS |
Urine output (ml) | 516 (402) | 557 (168) | 441 (286) | 361 (156) | NS |
Starch (ml) | 1125 (235) | 1018 (94) | 1000 (0) | 420 (179) | P < 0.001 |
Ringer’s lactate (ml) | 1475 (472) | 1438 (534) | 1333 (542) | 2295 (480) | P < 0.001 |
Erythrocytes (N; ml) | 5; 420 (277) | 1; 700 | 1; 300 | 6; 454 (282) | |
Plasma (N; ml) | 0 | 1; 500 | 1; 230 | 3; 417 (40) | |
Blood haemoglobin (g/L) | |||||
Before surgery | 128 (17) | 124 (24) | 127 (24) | 124 (22) | NS |
After surgery | 112 (15) | 115 (15) | 113 (19) | 111 (16) | NS |
Serum creatinine (μmol/L) | |||||
Before surgery | 69 (13) | 68 (17) | 65 (14) | 75 (14) | NS |
After surgery | 63 (12) | 61 (18) | 58 (12) | 64 (10) | NS |
Time in PACU (min) | 71 (25) | 60 (23) | 66 (34) | 97 (40) | P < 0.001 |
Paralytic ileus (days) | 3.2 (0.9) | 3.6 (1.4) | 2.7 (0.9) | 3.5 (1.1) | P = 0.054 |
Food intolerance (days) | 4.5 (1.9) | 4.6 (1.9) | 4.6 (2.4) | 6.5 (3.5) | P < 0.03 |
Complications per operation | 0.35 | 0.36 | 0.28 | 0.23 | NS |
Infectious complications (N) | 5 | 2 | 3 | 1 | |
Bleeding complications (N) | 1 | 3 | 1 | 1 | |
Length of hospital stay (days) | 13.0 (4.6) | 13.9 (2.6) | 13.3 (3.0) | 13.3 (4.7) | NS |