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Figure 5 | BMC Anesthesiology

Figure 5

From: Epinephrine reversed high-concentration bupivacaine- induced inhibition of calcium channels and transient outward potassium current channels, but not on sodium channel in ventricular myocytes of rats

Figure 5

Representative Ito traces obtained from ventricular myocyte groups: control, bupivacaine 100 μmol/L alone, and bupivacaine 100 μmol/L in combination with epinephrine 0.15 μg/ml. Family of current traces obtained by applying a series of 20ms test pulses of -40 mV to eliminate current through Na channels, which was then evoked by a series of 400 ms pulses ranging from -40 mV to 50 mV with a holding potential of -90 mV.

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