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Figure 4 | BMC Anesthesiology

Figure 4

From: Epinephrine reversed high-concentration bupivacaine- induced inhibition of calcium channels and transient outward potassium current channels, but not on sodium channel in ventricular myocytes of rats

Figure 4

The ICa-L current-voltage relationship in the absence of bupivacaine, with bupivacaine 100 μmol/L alone, and bupivacaine 100 μmol/L in combination with epinephrine 0.15 μg/ml. Bupivacaine 100 μmol/L present in the perfusate contributed to an upper shift of the current density - voltage curve without changing the activation potential and the curve shape. However, bupivacaine 100 μmol/L in combination with epinephrine 0.15 μg/ml increased the ICa-L current and moved the curve of ICa-L downward.

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BMC Anesthesiology

ISSN: 1471-2253

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