From: The etiology and outcome of non-traumatic coma in critical care: a systematic review
Study reference |  | Esquevin [6] | Forsberg [9] | Weiss [18] | Greer [14] | Hamel†[19] | Sacco [16] | Levy [15] | Tokuda [17] | Owolabi [12] | Obiako [10] | Sinclair [13] | Matuja [11] |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Structural | Stroke1 | 54 | 24 | 6 | 49 | 51 | 365 | 37 | 29 | 24 | 33 | 22 | 13 |
 | CNS infection | 2 | 2 | 3 | - | 6 | - | - | - | 14 | 10 | 19 | 51 |
 | Malignancy | 3 | 2 | - | - | 3 | - | - | <1 | 2 | 3 | 1 | - |
 | Other neurological causes | - | - | 1 | - | - | 7 | - | 11 | - | - | 1 | - |
Metabolic/Non-structural | Poisoning | - | 39 | 19 | - | <1 | - | - | 32 | - | 1 | 15 | 4 |
 | Epilepsy | 5 | 13 | 7 | - | - | - | - | 2 | 4 | - | - | - |
 | Post-anoxic coma | 3 | 7 | 23 | 40 | 31 | 36 | 42 | - | - | 4 | - | - |
 | Respiratory | - | 4 | 8 | - | - | - | - | 5 | - | - | - | - |
 | Infection | - | 4 | - | - | 9 | - | - | 4 | 19 | 11 | - | - |
 | Metabolic2 | 314 | 4 | 14 | - | 1 | 22 | - | 8 | 21 | 29 | 6 | 5 |
 | Hepatic encephalopathy | - | <1 | - | 2 | - | - | 10 | 2 | 8 | 6 | 1 | 20 |
 | Shock | - | - | 21 | - | <1 | - | - | - | - | - | - | - |
 | Unclassified3 | - | - | <1 | - | - | - | - | 2 | 8 | - | 22 | - |
 | Miscellaneous | 3 | - | 1 | 8 | 14 | - | 12 | <1 | - | - | - | 8 |
 | Eclampsia | - | - | - | - | - | - | - | - | - | - | 13 | - |