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Table 2 Clinical trials comparing PCV with VCV in obese patients

From: Perioperative lung protective ventilation in obese patients

Year

Author

Intervention

n

Weight (kg)

BMI

VT(mL)

Height (m)

VT/PBW

RR (breath/min)

PIP (cmH2O)

Ppl (cmH2O)

PEEP (cmH2O)

Outcome

             

Oxygenation

Ventilation

2008

Cadi [80]

PCV

18

121 (21)

44 (5)

613 (91)

 

11 (1.4)

18 (0.5)

26 (4)

26 (4)

5

↑

↑

  

VCV

18

119 (17)

45 (5)

573 (81)

 

10.2 (1.2)

18 (1.0)

33 (4)

27 (3)

5

  

2008

De Baerdemaeker [84]

PCV

12

111.7 (19.2)

38.6 (3.6)

612 (170)

1.70 (0.12)

NA

11.8 (1.8)

25.8 (1.6)

25.8 (1.6)

5

→

↓

  

VCV

12

117.4 (22.3)

41.4 (4.5)

645 (138)

1.68 (0.10)

NA

11.7 (1.2)

28.9 (4.2)

25.1 (3.7)

5

  

2008

Hans [83]

PCV

crossover

NA

crossover

650 (104)

 

10.0 (1.9)

12.2 (0.5)

21.5 (4.8)

21.5 (4.8)

0

→

→

  

VCV

40

NA

41.7 (5.8)

643 (100)

 

9.9 (1.8)

12.2 (0.5)

26.8 (5.2)

20.9 (4.6)

0

  
  1. (BMI = Body Mass Index; PBW = Predicted Body Weight; PIP = Peak Inspiratory Pressure; Ppl = plateau airway pressure; RR = Respiratory rate; VT = Tidal volume; ↑ = increased; ↓ = decreased; → = unchanged).