Table 3 Physiologic variables during the study of CO 2 reactivity on cerebral pial vessels under JM-1232(-) (n = 6) or sevoflurane anesthesia (n = 6)
From: The effects of topical and intravenous JM-1232(-) on cerebral pial microvessels of rabbits
JM Control | JM 40 ± 5 | JM 50 ± 5 | JM 30 ± 5 | S Control | S 40 ± 5 | S 50 ± 5 | S 30 ± 5 | |
|---|---|---|---|---|---|---|---|---|
MAP (mmHg) | 72 ± 13 | 72 ± 8 | 69 ± 7 | 63 ± 6 | 99 ± 7 | 95 ± 4 | 98 ± 4 | 95 ± 7 |
HR (bpm) | 249 ± 24 | 260 ± 14 | 272 ± 12 | 256 ± 4 | 242 ± 28 | 244 ± 45 | 248 ± 36 | 244 ± 43 |
RT(°C) | 39.8 ± 0.3 | 39.7 ± 0.3 | 39.9 ± 0.2 | 40.1 ± 0.1 | 40.2 ± 0.5 | 40.2 ± 0.5 | 40.0 ± 0.7 | 40.1 ± 0.6 |
pH | 7.42 ± 0.04 | 7.42 ± 0.05 | 7.32 ± 0.04† | 7.54 ± 0.05† | 7.40 ± 0.02 | 7.42 ± 0.03 | 7.33 ± 0.02* | 7.51 ± 0.02* |
PaCO2(mmHg) | 42 ± 2 | 42 ± 2 | 55 ± 2† | 31 ± 2† | 41 ± 2 | 41 ± 2 | 50 ± 2* | 32 ± 2* |
PaO2 (mmHg) | 451 ± 26 | 469 ± 15 | 437 ± 58 | 474 ± 25 | 480 ± 27 | 488 ± 32 | 476 ± 32 | 489 ± 34 |
Na+ (mEq/L) | 140 ± 2 | 139 ± 3 | 140 ± 2 | 139 ± 2 | 141 ± 1 | 141 ± 1 | 142 ± 1 | 142 ± 2 |
K+ (mEq/L) | 3.6 ± 0.4 | 3.7 ± 0.3 | 3.9 ± 0.4 | 3.9 ± 0.4 | 3.6 ± 0.4 | 3.6 ± 0.3 | 3.6 ± 0.2 | 3.4 ± 0.3 |
BS (mg/dl) | 126 ± 15 | 119 ± 11† | 120 ± 11 | 114 ± 8 | 135 ± 22 | 130 ± 15 | 135 ± 18 | 137 ± 12 |
BE | 2.8 ± 4.0 | 3.0 ± 4.0 | 2.2 ± 2.7 | 2.8 ± 4.3 | 1.2 ± 2.0 | 1.2 ± 2.0 | 1.5 ± 2.2 | 1.0 ± 2.2* |
Lactate (mmol/L) | 1.7 ± 0.4 | 2.0 ± 0.6 | 2.3 ± 0.9 | 3.3 ± 1.0† | 3.4 ± 2.0 | 3.2 ± 1.8 | 3.4 ± 1.9 | 4.1 ± 2.5 |