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Table 3 CSF penetration of individual patient

From: Drug concentrations in the serum and cerebrospinal fluid of patients treated with cefoperazone/sulbactam after craniotomy

Penetration

Peak cencentration (cefoperazone)

Trough concentration (cefoperazone)

Peak concentration (sulbactam)

Trough concentration (sulbactam)

1

13.0%

3.8%

9.4%

103.0%

2

6.5%

14.9%

22.7%

149.0%

3

3.7%

18.1%

6.9%

140.4%

4

1.3%

17.5%

1.6%

68.8%

5

17.1%

18.9%

8.3%

54.2%

6

5.9%

10.0%

16.9%

288.0%

7

20.0%

14.4%

37.6%

26.3%

8

1.4%

9.2%

4.5%

22.5%

X±SD

8.6%±7.2%

13.4%±5.3%

13.5%±11.9%

106.5%±87.5%