From: Increased cardiac index attenuates septic acute kidney injury: a prospective observational study
CI constant group (n = 13) | CI increased group (n = 16) | P value | |
---|---|---|---|
Age (years) | 78(69–86) | 75(65–83) | 0.29 |
Males n (%) | 7(54) | 8(50) | 1.00 |
Hypertension n (%) | 9(69) | 10(63) | 1.00 |
Diabetes mellitus n (%) | 5(38) | 4(25) | 0.69 |
Source of infection | |||
Lungs n (%) | 6(46) | 10(63) | 0.47 |
Abdomen n (%) | 7(54) | 4(25) | 0.14 |
Soft tissue n (%) | 0(0) | 1(6) | 1.00 |
Other n (%) | 0(0) | 1(6) | 1.00 |
APACHE score II | 24(24–30) | 23(19–27) | 0.13 |
SOFA score | 11(10–12) | 11(8–12) | 0.19 |
Mechanical ventilation n (%) | 10(77) | 13(81) | 0.70 |
Norepinephrine (ug/kg/min) | 0.3(0.1-0.4) | 0.2(0.2-0.4) | 0.36 |
Fluid Therapy | |||
Hydroxyethyl starch n (%) | 8(62) | 7(44) | 0.46 |
Colloid fluid n (%) | 11(85) | 13(81) | 1.00 |
Hydroxyethyl starch amount (ml/kg) | 11.7(7.1-18.6) | 7.9(7.1-10.0) | 0.20 |
Colloid fluid amount (ml/kg) | 13.8(7.1-20.0) | 8.2(5.0-10.6) | 0.20 |
Crystalloid fluid amount (ml/kg) | 26.8(15.7-34.7) | 28.3(18.9-42.8) | 0.51 |
Resuscitation fluid amount(ml/kg) | 35.8(27.6-53.6) | 36.1(25.8-52.4) | 0.86 |
EGDT period (hour) | 6.0(6.0 -7.0) | 6.0(5.0-6.0) | 0.27 |
Poor renal outcome n (%) | 8(62) | 1(6) | 0.003 |
AKI 2-3on admission n (%) | 6(46) | 4(25) | 0.27 |
Persistent AKI n (%) | 4(31) | 1(6) | 0.14 |
AKI 0-1on admission n (%) | 7(54) | 12(75) | 0.27 |
New AKI n (%) | 2(15) | 0(0) | 0.19 |
Use of renal-replacement therapy n (%) | 6(46) | 3(19) | 0.23 |
Days in ICU (days) | 8(6–14) | 8(7–19) | 0.98 |
28-day mortality n (%) | 6(46) | 5(31) | 0.47 |