Figure 4
Prior exposure of chorionic rings to sevoflurane blocks the effect of tetraethylammonium. Exposure of rings to 1 × 10-2 M tetraethylammonium transiently enhances resting tone. This effect is abolished following prior incubation in sevoflurane, demonstrating that sevoflurane blocks KCa++ channels (n = 10 rings per group). *P < 0.05 compared to control (Two way RM-ANOVA). † P < 0.05 compared to control at each timepoint (post hoc between group t test).