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Table 3 Univariable Cox Regression Model Results.

From: Nitrous oxide may not increase the risk of cancer recurrence after colorectal surgery: a follow-up of a randomized controlled trial

Variable

Category or Units

N

Hazard Ratio (95% C.I.)

P-Value

Gas

Nitrogen

107

1.0

0.56

 

Nitrous Oxide

97

1.14 (0.73, 1.79)

 

Age

10 Years

204

1.12 (0.91, 1.36)

0.29

Gender

Male

125

1.0

0.29

 

Female

79

1.27 (0.81, 2.00)

 

Hospital

AKH

181

1.0

0.07

 

SMZO

23

0.91 (0.45, 1.83)

 

Number of Nodes examined

1 Node

194

1.00 (0.90, 1.11)

0.98

Number of involved Nodes

1 Node

194

1.17 (1.12, 1.22)

< 0.001

Tumor Grade

G1

8

1.0

0.06

 

G2

142

1.35 (0.33, 5.58)

 
 

G3

43

2.60 (0.61, 11.1)

 
 

G4

1

--

 

Treatment of Tumor

None

86

1.0

0.01

 

Chemotherapy

60

1.84 (1.08, 3.16)

 
 

Radiation

24

0.82 (0.33, 2.00)

 
 

Both

28

2.39 (1.27, 4.50)

 

Log2(Preoperative CEA)

1 (Doubling)

144

1.32 (1.21, 1.44)

< 0.001

Site

Ascending

28

1.0

0.052

 

Sigmoid

58

2.99 (1.24, 7.25)

 
 

Rectum

89

2.23 (0.94, 5.32)

 
 

Cecum

23

1.36 (0.41, 4.45)

 
 

Multiple Colon Cancer

2

--

 

Dukes Classification

A

33

1.0

< 0.001

 

B

58

1.27 (0.38, 4.21)

 
 

C

71

5.23 (1.85, 14.7)

 
 

D

31

16.5 (5.72, 47.7)

 

Dissemination

No

153

1.0

< 0.001

 

Yes

48

7.82 (4.89, 12.5)

 

Adjacent Organ Invasion

No

142

1.0

< 0.001

 

Yes

59

2.28 (1.44, 3.61)

 

Neural Invasion

No

180

1.0

< 0.001

 

Yes

19

3.26 (1.84, 5.77)

 

Vessel Invasion

No

151

1.0

< 0.001

 

Yes

48

3.37 (2.11, 5.36)

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