Table 2 Data regarding requirement for postoperative analgesic, anti-emetic and anti-pruritic therapy and postoperative respiratory function.
Variable | 100 μg IT Morphine | 200 μg IT Morphine | 300 μg IT Morphine | P Value |
|---|---|---|---|---|
Median time (mins) to first request for Rescue Analgesia (interquartile range) | 442 (240, 1100) | 607 (343, 1440) | 857 (397, 1440) | 0.2 |
Number of patients that requested Rescue Analgesia | 17/20 | 12/20 | 12/20 | 0.1 |
Number of patients that requested anti-emetic therapy | 7/20 | 9/20 | 11/20 | 0.4 |
Time to first request for Antiemetic Therapy (mins) | 1117 ± 116 | 1037 ± 109 | 809 ± 138 | 0.2 |
Number of patients that required anti-pruritic therapy | 0/20 | 3/20 | 3/20 | 0.2 |
Incidence of Respiratory Depression (Total episodes of Resp Rate < 12) | 3/20 | 5/20 | 5/20 | 0.7 |
Number of episodes of mild arterial hypoxemia (SpO2 90 – 94%) | 8/20 | 9/20 | 8/20 | 0.9 |
Number of episodes of moderate arterial hypoxemia (SpO2 85 – 90%) | 1/20 | 0/20 | 1/20 | 0.6 |
Number of episodes of severe arterial hypoxemia (SpO2 < 85%) | 0/20 | 0/20 | 1/20 | 0.4 |
Median Sedation Score (interquartile range) | 1 (1, 4) | 1 (1, 4) | 1 (1, 4) | 0.9 |
Number of episodes of significant sedation (Total episodes of Sedation score = 5) | 4/20 | 3/20 | 4/20 | 0.9 |