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Table 3 Baseline Characteristics

From: Prevalence and impact of alcohol and other drug use disorders on sedation and mechanical ventilation: a retrospective study

 

AOD

No AOD

p

n

27

43

 

Age (years) (mean [95% CI])

50 [45.0; 55.8]

55 [50.6; 59.2]

0.20

Gender (n men/women)

21/6

15/28

<0.0001

Race (n African American/White/Asian)

20/7/0

22/19/2

0.12

APACHE II (mean [95% CI])

22 [18.2; 25.2]

26 [23.5; 29.0]

0.048

APACHE II excluding GCS (mean [95% CI])

13 [10.6; 17.1]

18 [15.1; 20.2]

0.07

SOFA (mean [95% CI])

8 [6.3; 9.3]

9 [7.5; 9.9]

0.33

Bilirubin* (mg/dl) (mean [95% CI])

2.2 [0.65; 3.85]

1.8 [0.52; 3.07]

0.65

Creatinine (mg/dl) (median, IQR)

1.1 [0.80; 2.20]

1.5 [1.10; 2.80]

0.10

P/F (mean [95% CI])

225 [177.4; 272.8]

218 [181.5; 254.2]

0.81

PEEP (cm H2O) (mean [95% CI])

5 [4.4; 6.4]

5 [3.9; 5.6]

0.30

Reason for mechanical ventilation

  

0.46

   Pneumonia/ALI

4

9

 

   Sepsis

1

4

 

   Delirium/Neurologic

7

10

 

   Asthma/COPD

3

4

 

   Upper airway obstruction

4

3

 

   Hemorrhagic shock

3

4

 

   Cardiac

1

4

 

   Cardiopulmonary arrest

1

2

 

   Drug overdose

3

0

 

   Other

0

3

 
  1. AOD: alcohol and other drug use disorders
  2. CI: confidence interval
  3. APACHE II: Acute Physiology and Chronic Health Evaluation II
  4. GCS: Glasgow Coma Score
  5. SOFA: Sequential Organ Failure Assessment
  6. *Bilirubin: Total bilirubin measured in 14 patients with AOD and 22 patients without AOD
  7. IQR: Interquartile range
  8. P/F: Partial pressure of oxygen divided by fraction of inspired oxygen
  9. PEEP: Positive end expiratory pressure