Table 2 Relationship between the intrinsic liver metabolic clearance (Tclr) and the fractional clearance of the total liver blood flow or the absolute steady state liver blood clearance for a standard male (20% fat, fraction free in plasma = 0.02).
From: Human physiologically based pharmacokinetic model for propofol
Tclr (liters/min) | Fraction Liver Blood Flow | Liver Clearance (liters/min) |
|---|---|---|
10 | 0.13 | 0.23 |
50 | 0.47 | 0.846 |
100 | 0.68 | 1.224 |
200 | 0.86 | 1.548 |
300 | 0.93 | 1.674 |
400 | 0.962 | 1.731 |
500 | 0.977 | 1.76 |