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Table 1 RIFLE criteria 11)

From: Usefulness of presepsin in the diagnosis of sepsis in patients with or without acute kidney injury

RIFLE classification

GFR criteria

Urine output criteria

Risk

Increased serum creatinine × 1.5 or GFR decrease > 25%

Urine output < 0.5 ml/kg/h × 6 hr

Injury

Increased serum creatinine × 2 or GFR decrease > 50%

Urine output < 0.5 ml/kg/h × 12 hr

Failure

Increased serum creatinine × 3 or GFR decrease > 75%, serum creatinine  4 mg/dL (acute rise > 0.5 mg/dL)

Urine output < 0.3 ml/kg/h × 24 hr or Anuria × 12 hr

Loss

Persistent ARF = complete loss of kidney function > 4 weeks

ESKD

End Stage Kidney Disease (>3 months)

  1. The criteria that lead to the worst possible classification should be used. RIFLE, Risk of renal dysfunction, Injury to the kidney, Failure of kidney function, Loss of kidney function and End-stage kidney disease; GFR, Glomerular Filtration Rate; ARF Acute Renal Failure.