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Figure 1 | BMC Anesthesiology

Figure 1

From: Pulmonary vascular permeability index and global end-diastolic volume: are the data consistent in patients with femoral venous access for transpulmonary thermodilution: a prospective observational study

Figure 1

Comparison of transpulmonary indicator dilution (TPTD) using femoral central venous catheter (CVC) instead of jugular or subclavian CVC. Obviously, the distribution volume for the indicator is augmented by the volume of vena cava inferior in case of femoral indicator injection. This results in diminished indicator concentration and overestimation of global enddiastolic volume GEDV. In single indicator dilution technique GEDV is calculated as difference of the total dilution volume (intrathoracic thermovolume ITTV) minus the sum of pulmonary blood volume PBV and extravascular lung water EVLW: GEDV = ITTV- (EVLW + PBV). The sum (PBV + EVLW) is thermed pulmonary thermovolume PTV, which is directly derived from the thermodilution curve. Therefore, it can be assumed not to be altered by the additional dilution volume of VCI participating in TPTD.

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