Table 3 Standardised intravenous paracetamol population pharmacokinetic parameter estimates

CLstd (L.h^-1.70 kg^-1)

16.7

0.246

0.231

15.2, 17.8

F_PREGCL

1.14

-

-

1.02, 1.27

Ffat_CL

1 FIX

-

-

-

F_ABDCL

0.715

-

-

0.548, 0.832

V1std (L.70 kg^-1)

24.6

0.555

-

21.7, 27.1

Q2std (L.h^-1.70 kg^-1)

67.3

0.257

-

56.1, 79.7

V2std ( L.70 kg^-1)

23.1

0.496

0.051

20.2, 26.1

Ffat_VOL

0.778

-

-

0.503, 0.933

F_ORTHOV2

0.649

-

-

0.485, 0.876

F_ICV2

1.51

-

-

1.07, 2.90

Fage_V2

0.838

-

-

0.702, 0.968

Q3

2.04

0.713

-

1.69, 2.81

V3

30.6

0.789

-

20.4, 64.3