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Table 4 Postoperative pain, recovery profiles and postoperative adverse effects

From: A prospective, randomized, double-blind, and multicenter trial of prophylactic effects of ramosetron on postoperative nausea and vomiting (PONV) after craniotomy: comparison with ondansetron

 

Group A (n = 41)

Group B (n = 44)

Group C (n = 42)

Pvalue

Postoperative 0–2 h

    

  Pain (VRS)

36 (0–80)

41 (0–90)

39 (0–100)

0.974

  PCA consumption (ml)

1.5 (0–7)

1.5 (0–8)

1.5 (0–5)

0.921

Postoperative 2–24 h

    

  Pain (VRS)

27 (0–100)

26 (0–85)

26 (0–70)

0.792

  PCA consumption (ml)

11 (0–46)

12 (20–75)

13 (0–78)

0.541

Postoperative 24–48 h

    

  Pain (VRS)

17 (0–80)

15 (0–60)

18(0–70)

0.589

  PCA consumption (ml)

16 (1–95)

26 (0.2-100)

22 (0–88)

0.345

Advervse events

    

  Drowsiness

4 (10)

5 (11)

2 (5)

0.528

  Dizziness

7 (17)

14 (32)

6 (14)

0.101

  Itching

1 (2)

1 (2)

0 (0)

0.604

  Others

1 (2)

0 (0)

0 (0)

0.347

  1. Group A; ondansetron 4 mg group. Group B; ondansetron 8 mg group. Group C; ramosetron 0.3 mg group. Values are expressed as median (range) or number of the patients (%).