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Table 3 Clinical data in patients without neuropsychological changes compared to data for patients with memory decline or psychological symptoms

From: Relationship between intraoperative regional cerebral oxygen saturation trends and cognitive decline after total knee replacement: a post-hoc analysis

 

No change (n = 75)

Memory decline (n = 15)

P*

Psychological symptoms (n = 25)

P*

Gender, male/female (%)

20/80

40/60

0.1756

24/76

0.7796

ASA score 1/2 (%)

21.3/78.7

13.3/86.7

0.7291

24/76

>0.999

Baseline right rSO2

65.71% (7.8%)

61.8% (9.2%)

0.0861

65.56% (6.8%)

0.9746

Baseline left rSO2

65.19% (6.2%)

64.13% (6.5%)

0.4149

65.64% (4.4%)

0.6908

Final right rSO2

59.99% (6.7%)

56.67% (6.8%)

0.1201

59.50% (6.7%)

0.7771

Final left rSO2

59.63% (6.8%)

58.93% (6.8%)

0.7311

58.29% (6.8%)

0.4201

Right rSO2 < 50% (n [%])

13 (17.3)

5 (33.3)

0.2845

7 (28)

0.3889

Right desaturation >20% (n [%])

14 (18.7)

4 (26.7)

0.7280

4 (16)

>0.999

Right desaturation >25% (n [%])

4 (5.3)

4 (26.7)

0.0226

3 (12)

0.3642

Left rSO2 < 50% (n [%])

13 (17.3)

1 (6.7)

0.4507

6 (24)

0.5612

Left desaturation >20% (n [%])

13 (17.3)

0 (0)

0.1171

6 (24)

0.5612

Left desaturation >25% (n [%])

5 (6.7)

0 (0)

0.5906

3 (12)

0.6771

Right-left ratio of rSO2 (n [%])

101.29 (6.17)

95.03 (8.51)

0.0005

100.46 (8.11)

0.2678

Mean right-left rSO2 difference

0.76 (4.16)

-2.87 (4.73)

0.0008

0.15 (4.66)

0.3498

Minimum temperature in°C

35.03 (0.78)

35.01 (0.75)

0.8163

34.88 (0.78)

0.4275

Mean temperature in °C

35.57 (0.72)

35.48 (0.67)

0.5459

35.44 (0.70)

0.4828

Blood loss (% of total volume)

47.33 (14.33)

38.89 (10.59)

0.0333

46.06 (21.43)

0.5950

Transfused patients (n [%])

37 (49.3)

3 (20)

0.0456

13 (52)

>0.999

No. of blood units transfused

0.81 (0.95)

0.33 (0.72)

0.0607

1 (1.08)

0.4638

Vasoactive drugs (atropine or ephedrine) (n [%])

20 (26.7)

4 (26.7)

>0.999

9 (36)

0.4438

Minimum perioperative Hb (g/dL)

8.72 (0.78)

9.19 (0.92)

0.0502

8.83 (1.19)

0.8146

Hb at discharge (g/dL)

9.09 (0.10)

9.67 (0.13)

0.0111

9.50 (0.18)

0.0491

CRP >0.8 mg/dl (n [%])

14 (18.6)

5 (33.3)

0.2531

10 (40)

0.0603

  1. Data are presented as means (SD), unless otherwise stated on each row as percentage of patients or number and percentage of patients.
  2. *Group with memory decline vs group with no changes, or group with psychological symptoms vs group with no changes.
  3. ASA = American Society of Anesthesiologists.
  4. CRP = C-reactive protein.
  5. Hb = hemoglobin.
  6. rSO2 = regional oxygen saturation.