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Figure 2 | BMC Anesthesiology

Figure 2

From: Ropivacaine attenuates endotoxin plus hyperinflation-mediated acute lung injury via inhibition of early-onset Src-dependent signaling

Figure 2

Effect of ropivacaine on acute lung injury. Acute lung injury was induced by either hyperinflation (HTV), bacterial lipopolysaccharide (LPS), or a combination of the two (“double-hit” model) in C57BL/6 wild type (C57 WT) mice. ALI was assessed by measuring (A) Excess lung water (ELW), (B) extravascular plasma equivalents (EVPE), (C) permeability index, and (D) myeloperoxidase activity as described in Methods. Values shown are mean ± SD (n = 7); # p < 0.05 vs. control (NS-NS-HTV); *p < 0.05 vs. LPS-NS-HTV.

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