Effect of ischemic and pharmacological preconditioning of lower limb muscle tissue on tissue oxygenation measured by near-infrared spectroscopy – a pilot study

Table 3 Effects of time and sevoflurane preconditioning on lower limb tissue oxygenation during sevoflurane preconditioning, ischemic preconditioning, clamping for surgery and postoperative reperfusion

	Sevoflurane preconditioning	Ischemic preconditioning	Clamping for surgery	Postoperative reperfusion
Time	0.73	< 0.0001*	< 0.0001*	< 0.0001*
Sevoflurane	0.54	0.95	0.34	0.7
Interaction of “Time”with “Sevoflurane”	0.67	< 0.0001*	0.68	0.008*

Effects of the factors “time” and “sevoflurane preconditioning (sevoflurane)” and the interaction of “Time” (time from the beginning of sevoflurane preconditioning, ischemic preconditioning, clamping for surgery or postoperative reperfusion) with “sevoflurane” (sevoflurane preconditioning before ischemic preconditioning) on tissue oxygen saturation during sevoflurane preconditioning, ischemic preconditioning, clamping for surgery and postoperative reperfusion (ANOVA with repeated measurements with side as inter subject factor). Tissue oxygen saturation was measured with near-infrared spectroscopy in the anterior tibial muscle. Significant effects are marked with asterisks (*).

ISSN: 1471-2253