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Table 3 Preoperative demographics and intraoperative data of patients 2 months before and after ventilator exchange after risk matching

From: Replacement of anesthesia machines improves intraoperative ventilation parameters associated with the development of acute respiratory distress syndrome

Preoperative variable

Before vent exchange (n = 864)

After vent exchange (n = 864)

p

Age (mean ± SD, yr)

49 ± 16

48 ± 16

0.656

Male (n,%)

358 (41%)

362 (42%)

0.884

Patient ASA 3,4 or 5 (n,%)

198 (23%)

188 (22%)

0.603

Emergent Case (n,%)

24 (3%)

16 (2%)

0.263

Predicted Body Weight (mean ± SD, kg)

64 ± 10.5

63 ± 10.5

0.294

Weight (mean ± SD, kg)

84 ± 23.5

84 ± 22.8

0.658

BMI (mean ± SD, kg/m 2 )

28.9 ± 7.4

29.0 ± 7.3

0.854

Smoker

   

 Former (n,%)

141 (16%)

134 (16%)

0.693

 Current (n,%)

138 (16%)

132 (15%)

0.74

Lung Disease (n,%)

3 (0.3%)

5 (0.6%)

0.726

Asthma (n,%)

71 (8%)

72 (8%)

1

COPD (n,%)

20 (2%)

19 (2%)

1

Diabetes (n,%)

86 (10%)

73 (8%)

0.381

Hypertension (n,%)

250 (29%)

230 (27%)

0.308

Coronary Artery Disease (n,%)

23 (3%)

18 (2%)

.527

Congestive Heart Failure (n,%)

12 (1%)

12 (1%)

1

Chronic Kidney Disease (n,%)

21 (2%)

20 (2%)

1

Hepatic Disease (n,%)

11 (1%)

11 (1%)

1

Alcohol Abuse (n,%)

27 (3%)

21 (2%)

0.464

Current Steroid Therapy (n,%)

24 (3%)

25 (3%)

1

Intraoperative variable

Before vent exchange (n = 864)

After vent exchange (n = 864)

p

Ventilatory Parameters (case medians)

   

 PIP (mean ± SD, cmH 2 O)

25.3 ± 5.7

20.3 ± 6.2

< 0.001

 PEEP (mean ± SD, cmH 2 O)

2.0 ± 1.3

1.5 ± 2.5

< 0.001

 ΔP (mean ± SD, cmH 2 O)

23.3 ± 5.4

18.8 ± 5.6

< 0.001

 RR (mean ± SD, breath per minute)

11.0 ± 2.3

10.5 ± 2.2

< 0.001

 Vt (mean ± SD, ml)

587 ± 146

559 ± 125

< 0.001

 Vt cc/kg PBW (mean ± SD, ml)

9.33 ± 2.22

8.98 ± 1.94

< 0.001

 FiO 2 (mean ± SD,%)

55.5 ± 16

51.2 ± 18

< 0.001

 cc/kg PBW ≤ 6 (n,%)

62 (7%)

63 (7%)

1

 cc/kg PBW ≤ 8 (n,%)

188 (22%)

219 (34%)

0.089

 Epochs of 10 minutes:

   

 PIP > 30 cmH2O

2.9 ± 6.4

1.4 ± 4.5

< 0.001

 Vt > 12 cc/kg PBW

1.7 ± 4.3

0.9 ± 3.6

< 0.001

Colloid use (n,%)

51 (5.9%)

47 (5.4%)

0.755

Crystalloid volume (median, 25 th ,75 th , ml)

1950 (1100, 2700)

1900 (1000,2500)

0.111

Case Length (mean ± SD, minutes)

198 ± 103

195 ± 104

0.531

Transfusion (n,%)

17 (2%)

15 (2%)

0.858

PRBC (n,%)

16 (2%)

15 (5%)

1

FFP (n,%)

2 (0.2%)

4 (0.5%)

0.683

Platelets (n,%)

2 (0.2%)

1 (0.1%)

1

  1. ASA = American Society of Anesthesiology Classification, BMI = body mass index, COPD = chronic obstructive pulmonary disease, PIP = peak inspiratory pressure, PEEP = positive end expiratory pressure, RR = respiratory rate, Vt = tidal volume, PBW = predicted body weight, FiO2 = fraction inspired oxygen, PBW = predicted body weight, PRBC = packed red blood cells, FFP = fresh frozen plasma.