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Table 1 Numerical scoring system used in the histopathological evaluation of renal ischemia [22]

From: Intravenous pretreatment with emulsified isoflurane preconditioning protects kidneys against ischemia/reperfusion injury in rats

Grade

Degree of the proximal convoluted tubule necrosis

0

Normal histology

1

Mitoses and necrosis of individual cells

2

Necrosis of individual cells in adjacent proximal convoluted tubules, with survival of surrounding tubules

3

Necrosis confined to the distal third of the proximal convoluted tubule with a band of necrosis extending across the inner cortex

4

Necrosis affecting all three segments of the proximal convoluted tubule

  1. The numerical scoring system for the histopathological evaluation of renal ischemia was first outlined by Jablonski et al. [22]. Histological assessment of kidney slices stained with hematoxylin-eosin was performed by a pathologist under a light microscope. Grade 0 indicates normal proximal convoluted tubule, Grade 4 indicates severly damaged proximal convoluted tubule.
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BMC Anesthesiology

ISSN: 1471-2253

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