Figure 2From: Therapeutic plasma exchange as rescue therapy in severe sepsis and septic shock: retrospective observational single-centre study of 23 patients Net fluid balance before and after first therapeutic plasma exchange (TPE). Net fluid balances as surrogate marker of septic vascular permeability are presented relating to the time of first TPE: 12Â hours preceding TPE, hours 0 to 12 after TPE, and hours 12 to 24 after TPE.Back to article page