Figure 1From: Therapeutic plasma exchange as rescue therapy in severe sepsis and septic shock: retrospective observational single-centre study of 23 patients Norepinephrine dose before, during and after first therapeutic plasma exchange (TPE) in non-survivors and survivors. Norepinephrine doses as surrogate marker of hemodynamic instability are presented relating to the time of first TPE: 3Â hours before initiation of TPE (h-3), initiation of TPE (h0), 3Â hours after TPE (h+3), 6Â hours after TPE (h+6), 9Â hours after TPE (h+9), 12Â hours after TPE (h+12), and 24Â hours after TPE (h+24).Back to article page