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Table 5 Comparison of clinical characteristics according to the quartile of NT-pro-BNP level

From: Usefulness of N-terminal pro-B-type natriuretic peptide in patients admitted to the intensive care unit: a multicenter prospective observational study

NT-pro-BNP (pg/mL)

< 104

104–341

341–1,637

> 1,637

p-value

Number of patients

360

360

360

360

 

Age, years

59 (49–69)

63 (52–72)

67 (55–76)

68 (56–75)

< 0.001

Male

250 (69.4)

223 (61.9)

213 (59.2)

220 (61.1)

0.024

Comorbidities

     

 Cirrhosis

47 (13.1)

62 (17.2)

29 (8.1)

19 (5.3)

< 0.001

 Hypertension

118 (32.8)

120 (33.3)

142 (39.4)

164 (45.6)

0.001

 IHD

18 (5.0)

29 (8.1)

49 (13.6)

64 (17.8)

< 0.001

 CHF

5 (1.4)

18 (5.0)

37 (10.3)

48 (13.3)

< 0.001

 DM

75 (20.8)

71 (19.7)

94 (26.1)

123 (34.2)

< 0.001

 CRF

8 (2.2)

16 (4.4)

35 (9.7)

85 (23.6)

< 0.001

 Cancer

130 (36.1)

164 (45.6)

144 (40.0)

106 (29.4)

< 0.001

Status at ICU admission

     

 Severe sepsis or septic shock

42 (11.7)

64 (17.8)

75 (20.8)

128 (35.6)

< 0.001

 ALI or ARDS

18 (5.0)

27 (7.5)

28 (7.8)

50 (13.9)

< 0.001

Admission category

     

 Medical

171 (47.5)

159 (44.2)

212 (58.9)

293 (81.4)

< 0.001

 Surgical

189 (52.5)

201 (55.8)

148 (41.1)

67 (18.6)

< 0.001

Reason for ICU admission

     

 Basic & observational**

166 (46.1)

174 (48.3)

156 (43.3)

87 (24.2)

< 0.001

 Cardiovascular

40 (11.1)

47 (13.1)

58 (16.1)

119 (33.1)

< 0.001

 Digestive

22 (6.1)

14 (3.9)

15 (4.2)

11 (3.1)

0.236

 Hepatic failure

29 (8.1)

39 (10.8)

14 (3.9)

4 (1.1)

< 0.001

 Neurologic

10 (2.8)

5 (1.4)

9 (2.5)

11 (3.1)

0.519

 Renal

1 (0.3)

2 (0.6)

3 (0.8)

15 (4.2)

< 0.001

 Respiratory

61 (19.6)

66 (18.3)

90 (25.0)

93 (25.8)

0.004

SAPS 3 score

50 (39–61)

55 (47–65)

58 (49–68)

68 (57–78)

< 0.001

SOFA score

5 (2–9)

6 (3–10)

6 (3–11)

10 (6–13)

< 0.001

ICU day

5 (3–12)

6 (4–16)

7 (4–17)

9 (4–20)

< 0.001

ICU mortality

28 (7.8)

55 (15.3)

76 (21.1)

113 (31.4)

< 0.001

Hospital day

16 (9–31)

17 (11–35)

17 (11–37)

19 (10–38)

0.106

Hospital mortality

41 (11.4)

66 (18.3)

107 (29.7)

139 (38.6)

< 0.001

  1. **Basic and observational intensive care was defined as the patient being in the ICU for surveillance, simple weaning from a ventilator after surgery, routine post-surgery care, or needing complex nursing care or monitoring drug intoxication without organ dysfunction.
  2. IHD = ischemic heart disease; CHF = congestive heart failure; CPF = chronic pulmonary disease; DM = diabetes mellitus; CRF = chronic renal failure; ICU = intensive care unit; ALI = acute lung injury; ARDS = acute respiratory distress syndrome.
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BMC Anesthesiology

ISSN: 1471-2253

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