Table 3 Impact of the pneumatic device on tracheal cuff pressure and microaspiration of gastric content
Variables | Continuous control of Pcuffn = 64 | Routine care n = 64 | p | OR (95% CI) |
|---|---|---|---|---|
Recording duration, h | 24 (23–24) | 24 (23–24) | 0.198 | |
Mean airway pressure, cm H2O | 13 (11–18) | 13 (11–17) | 0.216 | |
Mean Pcuff, cm H2O | 26 (24–28) | 22 (20–28) | 0.017 | |
Coefficient of Pcuff variation, % | 5 (3–12) | 19 (15–30) | <0.001 | |
Pcuff 20-30 cm H2O | ||||
yes | 64 (100) | 64 (100) | NA | |
% of recording time | 95 (70–99) | 44 (30–59) | <0.001 | |
Pcuff <20 or >30, cm H2O | ||||
Yes | 41 (66) | 64 (100) | <0.001 | |
Duration >30 min | 33 (51) | 64 (100) | <0.001 | |
Pcuff <20, cm H2O | ||||
Yes | 19 (29) | 60 (93) | <0.001 | 1.46 (1.23-1.73) |
Duration > 30 min | 16 (25) | 57 (89) | <0.001 | 2.63 (1.11-6.21) |
% of recording time | 0.01 (0–2) | 32 (9–54) | <0.001 | |
Pcuff >30, cm H2O | ||||
Yes | 33 (51) | 62 (96) | 0.001 | 1.57 (1.10-2.24) |
Duration >30 min | 25 (39) | 54 (84) | <0.001 | 1.50 (1.11-2.20 |
% of recording time | 0.9 (0–17) | 14 (4–30) | <0.001 | |
Microaspiration of gastric content | 32 (50) | 38 (59) | 0.238 | |
Pepsin, ng/mL | 185 (113–296) | 203 (120–338) | 0.171 | |
% of tracheal aspirates positive for pepsin | 29 (0–74) | 45 (0–100) | 0.162 |