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Figure 2 | BMC Anesthesiology

Figure 2

From: Xylazine-induced reduction of tissue sensitivity to insulin leads to acute hyperglycemia in diabetic and normoglycemic monkeys

Figure 2

Hyperglycemic effects of xylazine in fasted, ketamine-anesthetized cynomolgus monkeys. Panel A shows the time-dependent effects of xylazine in normoglycemic (open circle, n = 5) and insulin-dependent diabetic (solid circle, n = 5) monkeys. The dotted lines show the pre-xylazine glucose levels in normoglycemic and insulin-dependent diabetic monkeys. The time-dependent effects of xylazine on plasma insulin and glucagon are shown in panel B and C, respectively. ↑, the time point that xylazine (1–2 mg/kg) was injected intramuscularly. **, p < 0.01; vs. the baseline level at time zero.

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