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Table 1 Fluid challenge protocol

From: Global end-diastolic volume increases to maintain fluid responsiveness in sepsis-induced systolic dysfunction

CVP at start:

≤ 8 if PEEP ≤15

200 ml/10 min

 

≤ 12 if PEEP >15

200 ml/10 min

 

≤ 10 if PEEP ≤15

100 ml/10 min

 

≤ 14 if PEEP >15

100 ml/10 min

 

≤ 12 if PEEP ≤15

50 ml/10 min

 

≤ 16 if PEEP >15

50 ml/10 min

CVP during infusion:

increase >5

stop

CVP after 10 min:

increase ≤2

continue

 

2< increase ≤5

wait 10 min

 

increase >5

stop

CVP after 10 min waiting:

increase >2

stop

 

increase ≤2

repeat

  1. CVP Central venous pressure (mmHg), PEEP Positive end-expiratory pressure (cm H2O).