Table 1 Demographic characteristics and co-morbidities of patients with postoperative bleeding after cardiac surgery employing cardiopulmonary bypass
Variables | I Group n=38 | II Group n=41 | P value |
|---|---|---|---|
Demographic | |||
Sex (male/female) | 21/17 | 17/24 | 0.5 |
Age (years) | 67 ± 10 | 66 ± 10 | 0.7 |
EuroSCORE (%) | 4.8 ± 2 | 4.9 ± 1.7 | 0.2 |
BMI (kg/m2) | 27.6 ± 4.8 | 28.3 ± 4.6 | 0.5 |
EF (%) | 55 ± 8.8 | 56 ± 6.7 | 0.2 |
Hypertension (n) | 13 | 22 | 0.1 |
Previous myocardial infarction (n) | 13 | 13 | 1.0 |
Hypercholesterolemia (n) | 6 | 11 | 0.2 |
Pulmonary obstructive disease (n) | 5 | 3 | 0.48 |
Preoperative medication | |||
Aspirin (n) | 26 | 29 | 0.7 |
Clopidogrel (n) | 6 | 9 | 0.44 |
LMWH (n) | 31 | 25 | 0.42 |
Warfarin (n) | 2 | 1 | 0.6 |
Preoperative coagulation tests | |||
PT (%) | 87 ± 15 | 92 ± 12 | 0.15 |
APTT (sec.) | 34 ± 6 | 32 ± 4 | 0.05 |
Fibrinogen (g/L) | 4.4 ± 1.1 | 4.7 ± 1.5 | 0.25 |
PLT (x109/L) | 205 ± 39 | 225 ± 72 | 0.24 |
Surgical parameters | |||
CABG (n) | 16 | 17 | 0.9 |
Valve replacement (n) | 13 | 16 | 0.6 |
Combined surgery (n) | 8 | 9 | 0.8 |
CPB duration (min) | 106 ± 40 | 102 ± 41 | 0.8 |
Aorta occlusion time (min) | 66 ± 25 | 64 ± 29 | 0.4 |
Reperfusion time (min) | 35 ± 15 | 32 ± 15 | 0.5 |
Blood loss 24h (ml) | 812 ± 269 | 346 ± 102 | <0.001 |
Erythrocyte requirements during ICU stay (n) | 14 | 3 | 0.008 |
Plasma requirements during ICU stay (n) | 14 | 1 | 0.001 |
Cryoprecipitate requirements during ICU stay (n) | 7 | 1 | 0.03 |