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Table 3 Flow -chart of timing of the interventions and outcomes measures

From: Design and Organization of the Dexamethasone, Light Anesthesia and Tight Glucose Control (DeLiT) Trial: a factorial trial evaluating the effects of corticosteroids, glucose control, and depth-of-anesthesia on perioperative inflammation and morbidity from major non-cardiac surgery

 

Pre-op visit

Preop Immediate

Intra-op

Post-op immediately

POD1

POD2

POD3

Hospitalization

30-day

6, 12 months

  

Dexamethasone (8 mg)

  

Dexamethasone (4 mg)

Dexamethasone (2 mg)

    

Interventions

  

Depth of Anesthesia

       
   

Glucose Control

Glucose Control

      
        

Composite Primary outcome

Primary outcome (mortality)

 
        

Secondary outcomes

Secondary outcomes

Secondary outcomes

 

SF-12

       

SF-12

 

Outcomes

Christensen Fatigue Score

   

Christensen Fatigue Score

 

Christensen Fatigue Score

   
     

CAM ICU - twice daily

CAM ICU - twice daily

CAM ICU - twice daily

   
         

Phone call- vital status

Phone call- vital status

 

EKG

  

EKG

EKG

     
    

Cardiac Enzymes 3 × 8 hrs apart

     
  

CRP

  

CRP

CRP

    
  1. POD = post operative day; SF 12 = health-related quality of life measure; CRP = C-Reactive Protein; CAM ICU =Confusion Assessment Method-ICU
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BMC Anesthesiology

ISSN: 1471-2253

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