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Table 1 Active-controlled trials

From: Treatment of established postoperative nausea and vomiting: a quantitative systematic review

Ref

Validity score

Comparison

Surgery

Sponsorship

 

random blinding dropouts

(number of patients in brackets)

  

[28]

1/1/0

1) Ondansetron 8 mg iv (50)

2) Droperidol 1.25 mg iv (50)

Not reported

 

[29]

2/2/1

1) Ondansetron 0.1 mg/kg iv (16)

2) Droperidol 20 μg/kg iv (13)

Extraabdominal

 

[32]

2/2/0

1) Droperidol 1.25 mg iv (27)

2) Metoclopramide 10 mg iv (25)

3) Propofol 10 mg iv (26)

Mixed

 

[36]

1/1/0

1) Ondansetron 4 mg iv (380)

2) Metoclopramide 10 mg iv (366)

Not reported

Glaxo

[37]

1/1/0

1) Droperidol 20 μg/kg iv (40)

2) Granisetron 40 μg/kg iv (40)

3) Metoclopramide 0.2 mg/kg iv (40)

Laparoscopic

cholecystectomy

 

[38]

1/1/0

1) Droperidol 20 μg/kg iv (40)

2) Granisetron 40 μg/kg iv (40)

3) Metoclopramide 0.2 mg/kg iv (40)

Major

gynecological

 

[39]

1/1/1

1) Alizapride 100 mg iv (24)

2) Droperidol 1 mg iv (25)

3) Ondansetron 8 mg iv (25)

Gynecological

Glaxo