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  1. Research article

    A randomized trial of remote ischemic preconditioning and control treatment for cardioprotection in sevoflurane-anesthetized CABG patients

    Remote ischemic preconditioning (RIPC) efficacy is debated. Possibly, because propofol, which has a RIPC-inhibiting action, is used in most RIPC trials. It has been suggested that clinical efficacy is, however...

    Rianne Nederlof, Nina C. Weber, Nicole P. Juffermans, Bas A. M. J. de Mol, Markus W. Hollmann, Benedikt Preckel and Coert J. Zuurbier

    BMC Anesthesiology 2017 17:51

    Published on: 29 March 2017

  2. Research article

    Dexmedetomidine’s inhibitory effects on acetylcholine release from cholinergic nerves in guinea pig trachea: a mechanism that accounts for its clinical benefit during airway irritation

    Airway instrumentation can evoke upper airway reflexes including bronchoconstriction and cough which can cause serious complications including airway trauma, laryngospasm or bronchospasm which may in turn lead...

    Maya Mikami, Yi Zhang, Benjamin Kim, Tilla S. Worgall, Harald Groeben and Charles W. Emala

    BMC Anesthesiology 2017 17:52

    Published on: 29 March 2017

  3. Research article

    Effects of short-term hyperoxia on erythropoietin levels and microcirculation in critically Ill patients: a prospective observational pilot study

    The normobaric oxygen paradox states that a short exposure to normobaric hyperoxia followed by rapid return to normoxia creates a condition of ‘relative hypoxia’ which stimulates erythropoietin (EPO) productio...

    Abele Donati, Elisa Damiani, Samuele Zuccari, Roberta Domizi, Claudia Scorcella, Massimo Girardis, Alessia Giulietti, Arianna Vignini, Erica Adrario, Rocco Romano, Laura Mazzanti, Paolo Pelaia and Mervyn Singer

    BMC Anesthesiology 2017 17:49

    Published on: 23 March 2017

  4. Research article

    Continuous Non-invasive finger cuff CareTaker® comparable to invasive intra-arterial pressure in patients undergoing major intra-abdominal surgery

    Despite increased interest in non-invasive arterial pressure monitoring, the majority of commercially available technologies have failed to satisfy the limits established for the validation of automatic arteri...

    Irwin Gratz, Edward Deal, Francis Spitz, Martin Baruch, I. Elaine Allen, Julia E. Seaman, Erin Pukenas and Smith Jean

    BMC Anesthesiology 2017 17:48

    Published on: 21 March 2017

  5. Study protocol

    Midodrine as adjunctive support for treatment of refractory hypotension in the intensive care unit: a multicenter, randomized, placebo controlled trial (the MIDAS trial)

    Patients admitted to intensive care units (ICU) are often treated with intravenous (IV) vasopressors. Persistent hypotension and dependence on IV vasopressors in otherwise resuscitated patients lead to delay i...

    Matthew H. Anstey, Bradley Wibrow, Tharusan Thevathasan, Brigit Roberts, Khushi Chhangani, Pauline Yeung Ng, Alexander Levine, Alan DiBiasio, Todd Sarge and Matthias Eikermann

    BMC Anesthesiology 2017 17:47

    Published on: 21 March 2017

  6. Research article

    Changes in duration of action of rocuronium following decrease in hepatic blood flow during pneumoperitoneum for laparoscopic gynaecological surgery

    A moderate insufflation pressure and deep neuromuscular blockade (NMB) have been recommended in laparoscopic surgery in consideration of the possible reduction in splanchnic perfusion due to the CO2-pneumoperiton...

    Yang Liu, Wen Cao, Yu Liu, Yun Wang, Ren Lang, Yun Yue and An-Shi Wu

    BMC Anesthesiology 2017 17:45

    Published on: 20 March 2017

  7. Research article

    The effect of an electronic cognitive aid on the management of ST-elevation myocardial infarction during caesarean section: a prospective randomised simulation study

    Cognitive aids have come to be viewed as promising tools in the management of perioperative critical events. The majority of published simulation studies have focussed on perioperative crises that are characte...

    Michael St.Pierre, Bjoern Luetcke, Dieter Strembski, Christopher Schmitt and Georg Breuer

    BMC Anesthesiology 2017 17:46

    Published on: 20 March 2017

  8. Case report

    Case report of Pierre Robin sequence with severe upper airway obstruction who was rescued by fiberoptic nasotracheal intubation

    Pierre Robin sequence (PRS) refers to the association of micrognathia, glossoptosis, and airway obstruction. Cases with severe dyspnea due to upper airway obstruction immediately after birth are very rare. We ...

    Satoru Takeshita, Hiroko Ueda, Tatenobu Goto, Daisuke Muto, Hiroki Kakita, Kazuo Oshima, Takahisa Tainaka, Takayuki Ono, Yoshiaki Kazaoka and Yasumasa Yamada

    BMC Anesthesiology 2017 17:43

    Published on: 14 March 2017

  9. Research article

    The value of arterial pressure waveform cardiac output measurements in the radial and femoral artery in major cardiac surgery patients

    A relatively new uncalibrated arterial pressure waveform cardiac output (CO) measurement technique is the Pulsioflex-ProAQT® system. Aim of this study was to validate this system in cardiac surgery patients wi...

    A. van Drumpt, J. van Bommel, S. Hoeks, F. Grüne, T. Wolvetang, J. Bekkers and M. ter Horst

    BMC Anesthesiology 2017 17:42

    Published on: 14 March 2017

  10. Research article

    Tramadol vs dexmedetomidine for emergence agitation control in pediatric patients undergoing adenotonsillectomy with sevoflurane anesthesia: prospective randomized controlled clinical study

    This study was designed to compare the efficacy of an intraoperative single dose administration of tramadol and dexmedetomidine on hemodynamics and postoperative recovery profile including pain, sedation, emer...

    Nurdan Bedirli, Mehmet Akçabay and Ulku Emik

    BMC Anesthesiology 2017 17:41

    Published on: 11 March 2017

  11. Research article

    Changes in intraocular pressure and optic nerve sheath diameter in patients undergoing robotic-assisted laparoscopic prostatectomy in steep 45° Trendelenburg position

    To evaluate changes in intraocular pressure (IOP) and intracerebral pressure (ICP) reflected by the optic nerve sheath diameter (ONSD) in patients undergoing robotic-assisted laparoscopic prostatectomy (RALP) ...

    Sebastian Blecha, Marion Harth, Felix Schlachetzki, Florian Zeman, Christiane Blecha, Pierre Flora, Maximilian Burger, Stefan Denzinger, Bernhard M. Graf, Horst Helbig and Michael T. Pawlik

    BMC Anesthesiology 2017 17:40

    Published on: 11 March 2017

  12. Research article

    The effects of Y-27632 on pial microvessels during global brain ischemia and reperfusion in rabbits

    Global brain ischemia-reperfusion during propofol anesthesia provokes persistent cerebral pial constriction. Constriction is likely mediated by Rho-kinase. Cerebral vasoconstriction possibly exacerbates ischem...

    Noriyuki Shintani, Tadahiko Ishiyama, Masakazu Kotoda, Nobumasa Asano, Daniel I. Sessler and Takashi Matsukawa

    BMC Anesthesiology 2017 17:38

    Published on: 7 March 2017

  13. Research article

    Comparison of the myocardial protective effect of sevoflurane versus propofol in patients undergoing heart valve replacement surgery with cardiopulmonary bypass

    This study aimed to compare myocardial protective effects of anaesthesia with intravenous infusion of propofol versus inhalation of sevoflurane in patients undergoing heart valve replacement surgery with cardi...

    Xiao-Lin Yang, Dan Wang, Guo-Yuan Zhang and Xiao-Lan Guo

    BMC Anesthesiology 2017 17:37

    Published on: 4 March 2017

  14. Research article

    Effect of Dexmedetomidine combined with sufentanil for post- thoracotomy intravenous analgesia:a randomized, controlled clinical study

    Few studies have investigated the use of dexmedetomidine in patient-controlled intravenous analgesia (PCIA) after thoracic surgery. This study to evaluate the effect of dexmedetomidine combined with sufentanil...

    Chun-Shan Dong, Jun Zhang, Qiang Lu, Peng Sun, Jun-Ma Yu, Chao Wu and Hao Sun

    BMC Anesthesiology 2017 17:33

    Published on: 1 March 2017

  15. Research article

    The protective effects of propofol against CoCl2-induced HT22 cell hypoxia injury via PP2A/CAMKIIα/nNOS pathway

    Perioperative cerebral ischemia/hypoxia could induce hippocampal injury and has been reported to induce cognitive impairment. In this study, we used cobalt chloride (CoCl2) to build a hypoxia model in mouse hippo...

    Yan Lu, Wei Chen, Chen Lin, Jiaqiang Wang, Minmin Zhu, Jiawei Chen and Changhong Miao

    BMC Anesthesiology 2017 17:32

    Published on: 28 February 2017

  16. Research article

    Magnesium sulphate attenuate remifentanil-induced postoperative hyperalgesia via regulating tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord

    Remifentanil induced hyperalgesia (RIH) is characterized by stimulation evoked pain including allodynia and thermal hyperalgesia after remifentanil infusion. N-methyl-D-aspartate (NMDA) receptor was reported t...

    Jiehao Sun, Hai Lin, Guodong He, Wendong Lin and Jianping Yang

    BMC Anesthesiology 2017 17:30

    Published on: 21 February 2017

  17. Research article

    Administration of HES in elderly patients undergoing hip arthroplasty under spinal anesthesia is not associated with an increase in renal injury

    Hydroxyethyl starch (HES) is applied to achieve volume expansion during surgery; however, nephrotoxicity may be induced in patients with sepsis. Simultaneously, neutrophil gelatinase-associated lipocalin (NGAL...

    Yuanyuan Zhang, Yonghao Yu, Junya Jia, Wenli Yu, Rubin Xu, Licheng Geng and Ying Wei

    BMC Anesthesiology 2017 17:29

    Published on: 21 February 2017

  18. Research article

    Tracheal extubation in deeply anesthetized pediatric patients after tonsillectomy: a comparison of high-concentration sevoflurane alone and low-concentration sevoflurane in combination with dexmedetomidine pre-medication

    Dexmedetomidine can facilitate a smooth extubation process and reduce the requirement of sevoflurane and emergence agitation when administrated perioperatively. We aimed to observe the extubation process and t...

    Meiqin Di, Yuan Han, Zhuqing Yang, Huacheng Liu, Xuefei Ye, Hongyan Lai, Jun Li, Wangning ShangGuan and Qingquan Lian

    BMC Anesthesiology 2017 17:28

    Published on: 21 February 2017

  19. Research article

    The effect of deep muscle relaxation on the force required during Latissimus Dorsi dissection for breast reconstructive surgery: results of a prospective, double-blinded observational pilot study

    The use of neuromuscular blocking agents has previously been suggested to facilitate the dissection of the latissimus dorsi muscle during breast reconstructive surgery. The aim of this study was to quantify th...

    T. Ledowski, A. Goodwin-Walters, P. Quinn and M. Calvert

    BMC Anesthesiology 2017 17:27

    Published on: 21 February 2017

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