Table 2 Intra & postoperative data

Hydromorphone (mg):

 H1

 H6

 H12

 H18

 H24

1.5 (0.8)

3.4 (1.8)

4.7 (2.5)

6.4 (3.5)

7.6 (4.4)

1.7 (0.7)

3.0 (1.3)

4.4 (1.9)

6.0 (2.6)

8.1 (4.2)

-0.2 (-0.6 to 0.2)

0.4 (-0.5 to 1.4)

0.2 (-1.2 to 1.4)

0.4 (-1.4 to 2.2)

-0.3 (-2.8 to 2.1)

0.33^b

0.36^b

0.82^b

0.67^b

0.77^b

Fentanyl (mcg)

231 (143)

255 (142)

-24 (-103 to 55)

0.55^b

QoR-15:

 Preoperative

 Postoperative

 Delta QoR-15>=8

 Delta QoR-15 < 8

134 (10)

96 (25)

23 (88)

3 (12)

133 (14)

106 (20)

20 (83)

4 (17)

1.4 (-5.5 to 8.3)

-11 (-23 to 2)

0.05 (-0.14 to 0.24)

0. 68^b

0.10^b

0.909^a

Thorax VNRS at rest:

 Max

 Mean

6.0 (2.1)

3.3 (1.5)

5.4 (2.0)

2.7 (1.3)

0.6 (-0.6 to 1.7)

0.6 (-0.2 to 1.4)

0.34^b

0.12^b

Thorax VNRS at cough:

 Max

 Mean

7.1 (2.2)

4.9 (2.1)

6.6 (1.8)

4.6 (2.0)

0.5 (-0.6 to 1.6)

0.4 (-0.8 to 1.5)

0.39^b

0.54^b

Shoulder VNRS at rest:

 = 0, n (%)

 > 0, n (%)

11 (42)

15 (58)

13 (54)

11 (46)

0.12 (-0.16 to 0.39)

0.40^a

Mean

0.8 (1.1)

1.1 (1.4)

0 (0 to 0.8

0.29^d

Shoulder VNRS at cough:

 = 0, n (%)

 > 0, n (%)

11 (42)

15 (58)

14 (58)

10 (42)

0.16 (-0.11 to 0.43)

0.26^a

Mean

0.9 (1.5)

1.4 (1.6)

0 (0 to 1.2)

0.24^d

PONV score:

 1, n (%)

 2, n (%)

 3, n (%)

 Mean

14 (54)

9 (35)

3 (12)

1.0 [1.0-1.4]

15 (60)

8 (32)

2 (8)

1.0 [1.0-1.2]

-0.06 (-0.33 to 0.21)

0.03 (-0.23 to 0.28)

0.04 (-0.13 to 0.20)

0 (0 to 0)

0.87^a

0.54^d

Pruritus score:

 = 0, n (%)

 > 0, n (%)

24 (92)

2 (8)

25 (100)

0 (0)

0.08 (-0.08 to 0.25)

0.49^c

Mean

0.02 (0.08)

0.01 (0.04)

0 (0 to 0)

1^d

RSS score:

 2, n (%)

 3, n (%)

 4, n (%)

 5, n (%)

 Mean

15 (58)

4 (15)

7 (27)

0 (0)

2.1 (0.3)

15 (60)

3 (12)

6 (24)

1 (4)

2.1 (0.2)

-0.02 (-0.29 to 0.25)

0.03 (-0.15 to 0.22)

0.03 (-0.21 to 0.27)

-0.04 (-0.12 to 0.04)

0.05 (-0.09 to 0.20)

0.75^a

0.47^b